Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu+12 more
wiley +1 more source
Changes in IGF-I and -II, IGF Binding Protein, and IGF Receptor Transcript Abundance after Uterine Artery Ligation [PDF]
Wayne A. Price+3 more
openalex +1 more source
β‐hydroxy β‐methyl butyric acid (HMB), either as the free acid or in the form of its calcium salt, is a component of several dietary supplements marketed to enhance sports performance. We investigated the urinary excretion profile of HMB, also assessing the endogenous reference ranges of HMB in human urine samples from healthy volunteers (n = 20). Data
Cristian Camuto+3 more
wiley +1 more source
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis+2 more
wiley +1 more source
Phosphorylation of AMPKα at Ser485/491 Is Dependent on Muscle Contraction and Not Muscle-Specific IGF-I Overexpression. [PDF]
Chou CH, Barton ER.
europepmc +1 more source
18 SERUM SHBG/IGF-I DURING EARLY AND LATE PREPUBERTY IN CHILDREN WITH IDIOPHATHIC (I) AND ORGANIC (Or) GH DEFICIENCY [PDF]
Marta Ciaccio+2 more
openalex +1 more source
Effects of the Dietary Supplement 5α‐Hydroxy‐Laxogenin in the Orchiectomized Rat Model
The dietary supplement ingredient 5α‐hydroxy‐laxogenin was investigated in the castrated male rat for potential androgenic and anabolic effects. Moreover, androgen receptor binding of 5α‐hydroxy‐laxogenin was modelled by in silico docking. While molecular modelling supports androgen receptor binding, we observed neither androgenic nor anabolic effects ...
Daniel Derwand+4 more
wiley +1 more source
37 CORRELATION BETWEEN IGF-I AND STEROID LEVELS IN THE UMBILICAL CORD OF TERM NORMAL NEW (NB) [PDF]
M G F Osoria+5 more
openalex +1 more source
A head start: The relationship of placental factors to craniofacial and brain development
Abstract In recent years, the importance of placental function for fetal neurodevelopment has become increasingly studied. This field, known as neuroplacentology, has greatly expanded possible etiologies of neurodevelopmental disorders by exploring the influence of placental function on brain development.
Annemarie Jenna Carver+2 more
wiley +1 more source
Interpreting growth hormone and IGF-I results using modern assays and reference ranges for the monitoring of treatment effectiveness in acromegaly. [PDF]
Clemmons DR, Bidlingmaier M.
europepmc +1 more source