Insulin-Like Growth Factor II (IGF-II) Is More Potent Than IGF-I in Stimulating Cortisol Secretion from Cultured Bovine Adrenocortical Cells: Interaction with the IGF-I Receptor and IGF-Binding Proteins [PDF]
Although the stimulating effect of insulin-like growth factor I (IGF-I) on adrenal steroidogenesis has been well established, the role of IGF-II in the adult adrenal gland remains unknown.
Engelhardt, Dieter+3 more
core +1 more source
Insulin-Like Growth Factor (IGF)-I and -11 and IGFBinding Proteins-l, -2, and -3 in Children and Adolescents with Diabetes Mellitus: Correlation with Metabolic Control and Height Attainment. [PDF]
The putative effects of diabetes and metabolic control on circulating levels of insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) remain controversial.
Blum, Werner F.+6 more
core +1 more source
Blood parameter of Nellore steers submitted to different levels of feed intake
Blood parameters of 18 Nellore steers submitted to high concentrate diet in two sequential feeding regimes (Phase 1: restriction and Phase 2: ad libitum feed) were evaluated.
G. Aferri+5 more
doaj +1 more source
Identification and characterization of insulin-like growth factor receptors on adult rat cardiac myocytes: linkage to inositol 1,4,5-trisphosphate formation. [PDF]
Cultured cardiac myocytes from adult Sprague-Dawley rats express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose 6-phosphate (IGF-II/Man6P) receptors and respond to IGF-I with a dose-dependent accumulation of
Berg, Ingeborg+5 more
core +1 more source
The neuroprotective effects of intramuscular insulin-like growth factor-I treatment in brain ischemic rats. [PDF]
Brain ischemia leads to muscle inactivity-induced atrophy and may exacerbate motor function deficits. Intramuscular insulin-like growth factor I (IGF-I) injection has been shown to alleviate the brain ischemia-induced muscle atrophy and thus improve the ...
Heng-Chih Chang+4 more
doaj +1 more source
Bioactive IGF-I in Obesity [PDF]
Context: In obesity, total IGF-I is not reduced to the degree predicted by low GH levels, and free IGF-I levels are normal to high. Total and free IGF-I may not reflect IGF-I biologic activity, as immunoassays cannot account for the modifying effects of IGF binding proteins on interactions between IGF-I and its receptor.
Frystyk, J+4 more
openaire +2 more sources
Controlled Delivery of Sdf-1 Alpha and Igf-1: Cxcr4(+) Cell Recruitment and Functional Skeletal Muscle Recovery [PDF]
Therapeutic delivery of regeneration-promoting biological factors directly to the site of injury has demonstrated its efficacy in various injury models.
Farrar, Roger P.+6 more
core +1 more source
The ovarian response to a standard chronogest + eCG treatment with plasma levels of insulin, insulin-like growth factor-I (IGF-I), thyroids, non-esterified fatty acids (NEFA), OH-butyrate (BHB) and urea-N (PUN) was studied in lactating Awassi ewes (n ...
A. Marton+11 more
doaj +1 more source
Autophagy, an intracellular bulk protein degradation system in skeletal muscle, is increased under catabolic conditions resulting in muscle atrophy. This study aimed to investigate the effects of insulin, insulin-like growth factor (IGF)-I, and amino ...
Kazuki Nakashima, Aiko Ishida
doaj +1 more source
Untersuchung zur IGF-I-vermittelten Signaltransduktion in der humanen Karzinoidzellinie LCC-18 [PDF]
In dieser Arbeit wurde die Wachstumsregulation der Zellinie LCC-18 durch IGF-I untersucht. Die Zellinie LCC-18 wurde aus einem humanen Kolon-Karzinoid etabliert und zeigte stabile neuroendokrine Eigenschaften über eine Dauer von über 100 Zellpassagen ...
Göke, Rüdiger (Prof. Dr. med.)+1 more
core +1 more source