Results 71 to 80 of about 152,806 (342)
IGF-I, insulin and prostate cancer [PDF]
Arquivos Brasileiros de Endocrinologia & Metabologia, 2009 Prostate cancer is the second most frequent malignancy diagnosed in adult men. Androgens are considered the primary growth factors for prostate normal and cancer cells. However, other non-androgenic growth factors are involved in the growth regulation of prostate cancer cells.
Lima, Giovanna A. Balarini +4 more
openaire +5 more sources
Advanced Materials Technologies, EarlyView.A wireless bioelectronic ion pump platform is developed for controlled fluoxetine delivery for wound healing in a large mammal model. Over 3 days, treated wounds showed 37% greater re‐epithelialization and a 33% lower ratio of pro‐inflammatory to reparative macrophages.
Houpu Li +25 more
wiley +1 more source
Organ-specific expression of IGF-I during early development of bony fish as revealed in the tilapia, Oreochromis niloticus , by in situ hybridization and immunohistochemistry: indication for the particular importance of local IGF-I [PDF]
, 2018 The cellular sites of insulin-like growth factor I (IGF-I) synthesis in the early developing tilapia (0-140 days post fertilization, DPF) were investigated.
Baroiller, Jean-François +5 more
core
Astrocytes require insulin-like growth factor I to protect neurons against oxidative injury [PDF]
, 2016 Oxidative stress is a proposed mechanism in brain aging, making the study of its regulatory processes an important aspect of current neurobiological research.
Dávila, D. +5 more
core +1 more source
Advanced Therapeutics, EarlyView.Liquiritin enhances the osteogenic differentiation of BMSCs and promotes fracture healing through the activation of the ERK/JNK signaling pathway and by exerting antioxidant protective effects. Abstract Liquiritin, a flavonoid from Glycyrrhiza uralensis L., has diverse pharmacological properties, but its impact on fracture healing is unexplored.
Haijun Mao +6 more
wiley +1 more source
Insulin-Like Growth Factor-I and Epidermal Growth Factor Regulate Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3) in the Human Keratinocyte Cell Line HaCaT [PDF]
, 1995 The human keratinocyte cell line HaCaT has a basal phenotype and secretes an insulin-like growth factor (IGF) binding protein, IGFBP-3, which modulates its IGF-I response.
Werther, George A. +1 more
core +1 more source
Frontiers in Endocrinology, 2019 Glucagon, a key hormone for glucose homeostasis, can exert functional crosstalk with somatotropic axis via modification of IGF-I expression. However, its effect on IGF-I regulation is highly variable in different studies and the mechanisms involved are ...
Jin Bai +4 more
doaj +1 more source
Insulin-like growth factor-I E-peptide activity is dependent on the IGF-I receptor. [PDF]
PLoS ONE, 2012 Insulin-like growth factor-I (IGF-I) is an essential growth factor that regulates the processes necessary for cell proliferation, differentiation, and survival. The Igf1 gene encodes mature IGF-I and a carboxy-terminal extension called the E-peptide.
Becky K Brisson, Elisabeth R Barton
doaj +1 more source
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2013 Numerous studies have reported associations between IGF-I and other extra cellular matrix (ECM) proteins, including fibronectin (FN), integrins, IGF-binding proteins (IGFBPs) and through IGFBPs, with vitronectin (VN). Nevertheless, the precise nature and mechanisms of these interactions are still being characterised.
Sivaramakrishnan, Manas +6 more
openaire +4 more sources
Advances in Microfluidic Cochlea‐On‐A‐Chip
Advanced Science, EarlyView.This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen +10 more
wiley +1 more source