Results 71 to 80 of about 14,093,235 (401)

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Insulin-like Growth Factors Regulate Neuronal Differentiation and Survival

Neurobiology of Disease, 1997
Insulin-like growth factor I (IGF-I) and IGF-II are potent trophic factors for motor and sensory neurons and glial cells. The actions of IGF-I and IGF-II are mediated via the IGF-I receptor (IGF-IR).
Eva L. Feldman, Kelli A. Sullivan, Bhumsoo Kim, James W. Russell   +3 more
doaj   +1 more source

Influence of vitamin D on biomechanical microstructure and properties of patients with hip fracture. [PDF]

, 2017
Valorar niveles séricos de 25-hidroxivitamina D -25(OH)D-, hormonas con influencia sobre el metabolismo óseo (parathormona -PTH- y factor de crecimiento insulínico -IGF-I-), marcadores de remodelado óseo (MRO) (telopéptido carboxilo-terminal del colágeno
(Coordinador), Giner García, Mercedes, Montoya García, María José, Pérez Cano, Ramón, Vázquez Gámez, María de los Ángeles   +4 more
core  

The in vitro and in vivo effects of human growth hormone administration on tumor growth of rats bearing a transplantable rat pituitary tumor (7315b) [PDF]

, 1990
The direct effects of human GH and IGF-I on PRL secretion and cell proliferation were studied on PRL secreting rat pituitary tumor 7315b cells in vitro, as well as the effects in vivo of human GH administration on body weight, IGF-I levels and tumor size
Binnerts, A. (Arjen), Hofland, L.J. (Leo), Koetsveld, P.M. (Peter) van, Lamberts, S.W.J. (Steven), Uitterlinden, P. (Piet)   +4 more
core   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Insulin-like growth factor and growth hormone receptor in postpartum lactating beef cows Fator de crescimento semelhante à insulina e receptor do hormônio do crescimento no pós-parto de vacas de corte

Pesquisa Agropecuária Brasileira, 2010
The objective of this study was to evaluate the plasma concentrations of insulin-like growth factor-I (IGF-I), and the mRNA hepatic expression of IGF-I and of the growth hormone receptors GHR and GHR 1A, in postpartum beef cows.
Augusto Schneider, Luiz Francisco Machado Pfeifer, Lucas Teixeira Hax, Giane Regina Paludo, Francisco Augusto Burkert Del Pino, Nelson José Laurino Dionello, Marcio Nunes Corrêa   +6 more
doaj   +1 more source

PERK eIF2α kinase regulates neonatal growth by controlling the expression of circulating insulin-like growth factor-I derived from the liver [PDF]

, 2003
Humans afflicted with the Wolcott-Rallison syndrome and mice deficient for PERK (pancreatic endoplasmic reticulum eIF2α kinase) show severe postnatal growth retardation.
CAVENER Douglas R, FRANK Ami, GABAI Aryn, IIDA Kaori, LI Sheng’ai, LI Yulin, LIANG Shun-Hsin, O’NEIL Jeff, ROSEN Clifford J, ZAMBITO Frank, ZHANG Peichuan, 香穂里 飯田   +11 more
core   +2 more sources

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

Aspects of Growth Hormone and Insulin-Like Growth Factor-I Related to Neuroprotection, Regeneration, and Functional Plasticity in the Adult Brain

The Scientific World Journal, 2006
Apart from regulating somatic growth and metabolic processes, accumulating evidence suggests that the growth hormone (GH)/insulin-like growth factor-I (IGF-I) axis is involved in the regulation of brain growth, development, and myelination.
N. David Åberg, Katarina Gustafson Brywe, Jörgen Isgaard   +2 more
doaj   +1 more source

Aging Impairs IGF-I Receptor Activation and Induces Skeletal Resistance to IGF-I

Journal of Bone and Mineral Research, 2007
Abstract IGF-I plays an important anabolic role in stimulating bone formation and maintaining bone mass. We show that the pro-proliferative, anti-apoptotic, and functional responses to IGF-I in bone and BMSCs decrease with aging. These changes are associated with impaired receptor activation and signal transduction through the MAPK and ...
Jay J, Cao, Pamela, Kurimoto, Benjamin, Boudignon, Clifford, Rosen, Florence, Lima, Bernard P, Halloran   +5 more
openaire   +2 more sources