Results 31 to 40 of about 5,200,432 (243)

Heterogeneity for IGF-II production maintained by public goods dynamics in neuroendocrine pancreatic cancer [PDF]

open access: yes, 2015
The extensive intratumor heterogeneity revealed by sequencing cancer genomes is an essential determinant of tumor progression, diagnosis, and treatment.
Daniela A. Ferraro   +6 more
core   +1 more source

Id1-Induced IGF-II and Its Autocrine/Endocrine Promotion of Esophageal Cancer Progression and Chemoresistance—Implications for IGF-II and IGF-IR–Targeted Therapy

open access: yesClinical Cancer Research, 2014
Purpose: To investigate the autocrine/endocrine role of Id1-induced insulin-like growth factor-II (IGF-II) in esophageal cancer, and evaluate the potential of IGF-II- and IGF-type I receptor (IGF-IR)-targeted therapies.
Bin Li   +7 more
semanticscholar   +1 more source

Insulin-Like Growth Factor (IGF)-I and -11 and IGFBinding Proteins-l, -2, and -3 in Children and Adolescents with Diabetes Mellitus: Correlation with Metabolic Control and Height Attainment. [PDF]

open access: yes, 1995
The putative effects of diabetes and metabolic control on circulating levels of insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) remain controversial.
Blum, Werner F.   +6 more
core   +1 more source

Insulin-like Growth Factor-II (IGF-II) and IGF-II Analogs with Enhanced Insulin Receptor-a Binding Affinity Promote Neural Stem Cell Expansion*

open access: yesJournal of Biological Chemistry, 2014
Background: IGF-II promotes neural stem cell (NSC) proliferation and self-renewal. Results: IGF-II analogs are useful for elucidating the receptors responsible for NSC expansion. Conclusion: F19A expands NSCs via IR-A.
Amber N. Ziegler   +4 more
semanticscholar   +1 more source

Expression of Intratumoral IGF-II Is Regulated by the Gene Imprinting Status in Triple Negative Breast Cancer from Vietnamese Patients

open access: yesInternational Journal of Endocrinology, 2015
African American women suffer higher incidence and mortality of triple negative breast cancer (TNBC) than Caucasian women. TNBC is very aggressive, causing the worst clinical outcome.
Vinodh Kumar Radhakrishnan   +5 more
doaj   +1 more source

Prenatal cocaine exposure impairs cognitive function of progeny via insulin growth factor II epigenetic regulation

open access: yesNeurobiology of Disease, 2015
Studies have showed that prenatal cocaine exposure (PCOC) can impair cognitive function and social behavior of the offspring; however, the mechanism underlying such effect is poorly understood.
Qian Zhao   +17 more
doaj   +1 more source

Transfer of insulin-like growth factors I and II from plasma to lymph in young goats [PDF]

open access: yes, 1992
The plasma clearance of intravenously injected '25I-labelled insulin-like growth factor I (IGFI, n = 13) and IGF-II (n = 12) and their transfer into lymph draining the foreleg of 3 5- to 8- week-old British Saanen goats was studied.
Baucells Sánchez, María Dolores   +2 more
core   +2 more sources

Extreme Hypoglycaemia in Anaplastic Large Cell Lymphoma

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2017
Introduction: Hypoglycaemia associated with non-islet cell tumours (NICTH) is a rare entity in patients with extra-pancreatic malignancies, mostly attributed to large mesenchymal or epithelial tumours.
Lidor Akavia, Ilan Krauze
doaj   +1 more source

Insulin-like growth factor II acts through an endogenous growth pathway regulated by imprinting in early mouse embryos [PDF]

open access: yes, 1992
We present evidence that insulin-like growth factor II (IGF-II) mediates growth in early mouse embryos and forms a pathway in which imprinted genes influence development during preimplantation stages, mRNA and protein for IGF-II were expressed in ...
Behrendtsen, Ole   +5 more
core   +2 more sources

Temporal expression pattern of the insulin-like growth factor II and fibroblast growth factor transcripts in avian embryogenesis [PDF]

open access: yes, 2008
In this study, the abundance of IGF-II and bFGF transcripts was estimated in the chicken embryos using the competitive RT-PCR analysis. Significant enhancements in the abundance of IGF-II mRNA were observed at stages HH1 and 5, and a new accumulation in ...
ALVARES, Lúcia Elvira   +2 more
core   +3 more sources

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