Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007 The presence of annexin II (Ann-II) during the initial stages of bovine embryo development and the regulation of Ann-II expression by retinol and insulin-like growth factor I (IGF-I) were studied.
L.F.S. Costa +5 more
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IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells [PDF]
, 2012 The cysteine-type peptidase cathepsin X is highly upregulated in several cancers and presumably promotes tumor invasion through bypassing cellular senescence. Here, we present first evidence that the underlying mechanism may involve the regulation of the
Bunsen, Thea +3 more
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The Involvement of the GH/IGF-I Axis in Cognitive Functions of Adult Patients and Healthy Subjects [PDF]
, 2012 We describe the synthesis and purification of two functional peptides, namely human insulin-like growth factor II (IGF-II) and Xenopus laevis magainin II in Hansenula polymorpha after their synthesis as hybrid proteins fused to the C terminus of ...
Deijen, J.B., Drent, M.L., Driel, M.I.
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mAbsSystemic target engagement constrains the therapeutic index of many antibody drugs, particularly in inflammatory disease and immuno-oncology. Protease-cleavable masking can localize activity to disease sites, but existing approaches often tradeoff ...
Lihua Shi +4 more
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Placental determinants of fetal growth: identification of key factors in the insulin-like growth factor and cytokine systems using artificial neural networks [PDF]
, 2008 Background Changes and relationships of components of the cytokine and IGF systems have been shown in placenta and cord serum of fetal growth restricted (FGR) compared with normal newborns (AGA).
Maria E Street +50 more
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The International Journal of Biological Markers, 2008 Insulin-like growth factors (IGFs) are mitogens for numerous types of cells including cancer cells. The aim of this work was to analyze some of the components of the IGF system to assess which could be potential clinical biomarkers for monitoring ...
O. Nedić +3 more
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Obstetrics and Gynecology International, 2010 Objective. To compare the difference of imprinting status of insulin-like growth factor II (IGF-II) gene in villus between normal embryo development group and abnormal embryo development group and to investigate the relationship between karyotype and ...
Jianhong Chen +4 more
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Frontiers in ZoologyThe wolf (Canis lupus) is a species of great conservation interest and has recently highlighted management challenges throughout Europe. Over the past 50 years, the establishment of National Parks, forest cover changes as well as the expansion of wild ...
Maria Buglione +5 more
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Zmiany w stężeniach insulinopodobnych czynników wzrostu IGF-1 i IGF-2 i białek wiążących BP-2 i BP-3 w czasie leczenia ostrej białaczki limfoblastycznej [PDF]
Pediatric Endocrinology, Diabetes and Metabolism, 2004 Cel pracy: Ocena dynamiki zmian w wartościach insulinopodobnych czynników wzrostu: IGF-1 i IGF-2 i białek wiążących: IGFBP-2 i IGFBP-3 w surowicy krwi dzieci z ostrą białaczką limfoblastyczną (ALL) w trakcie leczenia przeciwnowotworowego.
Maryna Krawczuk-Rybak +2 more
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A daganatos és stroma sejtek közötti interakciók vizsgálata a gyomorrák kialakulásában és progressziójában. Klinikai és kísérletes vizsgálatok. = The role of tumor-stroma interactions in the initiation and progression of gastric cancer. Clinical and experimental studies. [PDF]
, 2013 Kísérleteink azt mutatták, hogy a humán gyomor miofibroblaszt sejtek (HGM) száma a rákos szövetben nagy mértékben megnövekedett, továbbá morfológiai és szerkezeti károsodást szenvedtek a normál szöveti sejtekhez képest.
Czepán, Mátyás +12 more
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