Results 51 to 60 of about 224,363 (192)
Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells
eLife, 2017 Metabotropic glutamate receptors (mGluRs) are mandatory dimers playing important roles in regulating CNS function. Although assumed to form exclusive homodimers, 16 possible heterodimeric mGluRs have been proposed but their existence in native cells ...
David Moreno Delgado +13 more
doaj +1 more source
Níveis sérico de IGF-I e IGFBP-3 em pacientes admitidos por complicações da cirrose hepática [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Mestrado Profissional Associado à Residência Médica em Cuidados Intensivos e PaliativosIntrodução: IGF-I e IGFBP-3 fazem parte do sistema IGF e, por terem ...
Ronsoni, Marcelo Fernando
core
, 2014 Jahresbericht 2013, über die Forschungs- und Lehrtätigkeit des Instituts für Geoinformatik und Fernerkundung ...
Ehlers, Manfred
core +1 more source
Phospho-Tau Signature During Mitosis: AT8, p-T217 and p-S422 as Key Phospho-Epitopes
CellsTau was initially identified as a microtubule-binding protein critical for microtubule stabilization. It is also a pathological hallmark of tauopathies, a group of neurodegenerative diseases that include Alzheimer’s disease. Under pathological conditions,
Marion Goussard +9 more
doaj +1 more source
Re-expression of IGF-II is important for beta cell regeneration in adult mice [PDF]
, 2012 Background The key factors which support re-expansion of beta cell numbers after injury are largely unknown. Insulin-like growth factor II (IGF-II) plays a critical role in supporting cell division and differentiation during ontogeny but its role in the
Nattkemper, Tim Wilhelm ; https://orcid.org/ +37 more
core +2 more sources
Procedures for Culturing and Genetically Manipulating Murine Hippocampal Postnatal Neurons
Frontiers in Synaptic Neuroscience, 2020 Neuronal hippocampal cultures are simple and valuable models for studying neuronal function. While embryonic cultures are widely used for different applications, mouse postnatal cultures are still challenging, lack reproducibility and/or exhibit ...
Enora Moutin +11 more
doaj +1 more source
AKT signaling mediates IGF-I survival actions on otic neural progenitors [PDF]
, 2012 Background: Otic neurons and sensory cells derive from common progenitors whose transition into mature cells requires the coordination of cell survival, proliferation and differentiation programmes.
Sanchez-Calderon, Hortensia +19 more
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, 2019 (A) and IGF-I to IGFBP-3 ratio (B) in a subgroup of patients with supra-physiological level of IGF-I. The boxes represent interquartile ranges and the whiskers represent 10th and 90th percentiles.
Jae Hyun Kim (665252) +9 more
core +1 more source
Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum
Nature Communications, 2020 Striatal dopaminoceptive neurons are molecularly and functionally heterogeneous. Here, the authors provide the translatome of D2R striatal neurons and identified hundreds of region specific molecular markers as well as testing their resource to shed ...
Emma Puighermanal +17 more
doaj +1 more source
A multi-cohort study of polymorphisms in the GH/IGF axis and physical capability: the HALCyon programme [PDF]
, 2012 Background: Low muscle mass and function have been associated with poorer indicators of physical capability in olderpeople, which are in-turn associated with increased mortality rates.
Kumari, Meena +101 more
core +1 more source