Results 31 to 40 of about 457,033 (338)
Clinical Significance of 7s IgM in Monoclonal IgM Diseases [PDF]
BMJ, 1971 The sera from 117 patients with diseases associated with a high production of monoclonal IgM were analysed for the presence of low molecular weight (7s) IgM by using a simple thin-layer Sephadex technique. 7s IgM was found in the sera of patients with myelomata (66%), lymphomata (45%), and Waldenström's macroglobulinaemia (20%), but was absent from the
P M, Carter, J R, Hobbs
openaire +2 more sources
, 2019 The excessive dispersion measure (DM) of fast radio bursts (FRBs) has been proposed to be a powerful tool to study intergalactic medium (IGM) and to perform cosmography.
Gao, He +5 more
core +2 more sources
, 1998 Using the cosmic virial theorem, Press-Schechter analysis and numerical simulations, we compute the expected X-ray background (XRB) from the diffuse IGM with the clumping factor expected from gravitational shock heating.
Cooray A. +5 more
core +3 more sources
IgM Myeloma: An IgM Gammopathy Distinct from Waldenstrom's Macroglobulinemia [PDF]
Hematology, 2001 A 65-year-old patient with an IgM gammopathy, plasma cell infiltration of the bone marrow, lytic lesions of the skeleton, and symptoms of hyperviscosity was evaluated. A diagnosis of IgM myeloma was made. Treatment for multiple myeloma was initiated and resulted in a significant clinical response. There is ongoing debate whether IgM myeloma exists as a
L T, Nordquist +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Frontiers in Genetics, 2015 DNA replication and transcription are vital cellular processes during which the genetic information is copied into complementary DNA and RNA molecules.
Alessandra eBrambati +5 more
doaj +1 more source
Evaluation of serum immunoglobulin (IgG, IgM, IgA) in oral cancer patients – A case control study
Journal of Indian Academy of Oral Medicine and Radiology, 2021 Background: Very few studies have been done to evaluate the level of serum immunoglobulins (IgG, IgM, and IgA) in patients with oral cancer as tumor markers. Aims and Objectives: The aim of this study was to estimate the serum immunoglobulins level (IgG,
Vivek M Tarsariya +5 more
doaj +1 more source
The Ionizing Efficiency of the First Stars [PDF]
, 2003 We investigate whether a single population of first stars could have influenced both the metal enrichment and reionization of the high-redshift intergalactic medium (IGM), by calculating the generated ionizing radiation per unit metal yield as a function
Truran, James W., Venkatesan, Aparna
core +3 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Frontiers in Oncology, 2019 Herein, ruthenium complexes containing heterocyclic thioamidates [Ru(mmi)(bipy)(dppb)]PF6 (1), [Ru(tzdt)(bipy)(dppb)]PF6 (2), [Ru(dmp)(bipy)(dppb)]PF6 (3) and [Ru(mpca)(bipy)(dppb)]PF6 (4) were investigated for their cellular and molecular effects in ...
Sara P. Neves +10 more
doaj +1 more source