Results 21 to 30 of about 1,096,946 (288)

Reciprocal regulation of IL-33 receptor–mediated inflammatory response and pulmonary fibrosis by TRAF6 and USP38

Proceedings of the National Academy of Sciences of the United States of America, 2022
Significance IL-33R mediates local inflammatory responses and plays crucial roles in the pathogenesis of immune diseases. In this study, we identified USP38, which negatively regulates IL-33-triggered signaling by mediating K27-linked deubiquitination of
Xue-Mei Yi, Mi Li, Yun-Da Chen, H. Shu, Shu Li   +4 more
semanticscholar   +1 more source

IL-33, an Alarmin of the IL-1 Family Involved in Allergic and Non Allergic Inflammation: Focus on the Mechanisms of Regulation of Its Activity

Cells, 2021
Interleukin-33 (IL-33) is a member of the interleukin-1 (IL-1) family that is expressed in the nuclei of endothelial and epithelial cells of barrier tissues, among others.
C. Cayrol
semanticscholar   +1 more source

Interleukin-22 and interleukin-33 show up-regulated levels in the serum of patients with mild/moderate Coronavirus disease 2019

Beni-Suef University Journal of Basic and Applied Sciences, 2023
Background This study analyzed serum concentrations of interleukin (IL)-22 and IL-33 (pro-inflammatory and anti-inflammatory cytokines) in 90 patients with mild/moderate coronavirus disease 2019 (COVID-19) and 90 healthy controls.
Abdulraheem Y. Majeed, Nor Effa S. Zulkafli, Ali H. Ad’hiah   +2 more
doaj   +1 more source

Role of IL-33 and ST2 signalling pathway in multiple sclerosis: expression by oligodendrocytes and inhibition of myelination in central nervous system [PDF]

, 2016
Recent research findings have provided convincing evidence indicating a role for Interleukin-33 (IL-33) signalling pathway in a number of central nervous system (CNS) diseases including multiple sclerosis (MS) and Alzheimer’s disease.
Allan, Debbie, Barnett, Susan C., Elliott, Christina, Fairlie-Clarke, Karen J., Jiang, Hui-Rong, Lassmann, Hans, Linnington, Christopher, Schuh, Cornelia   +7 more
core   +2 more sources

Interleukin‐33 (IL‐33): A nuclear cytokine from the IL‐1 family

Immunological Reviews, 2018
Interleukin‐33 (IL‐33) is a tissue‐derived nuclear cytokine from the IL‐1 family abundantly expressed in endothelial cells, epithelial cells and fibroblast‐like cells, both during homeostasis and inflammation.
C. Cayrol, J. Girard
semanticscholar   +1 more source

PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions

Nature Communications, 2021
Group 2 innate lymphoid cells (ILC2s) play a critical role in protection against helminths and in diverse inflammatory diseases by responding to soluble factors such as the alarmin IL-33, that is often overexpressed in cancer.
G. Ercolano, Alejandra Gómez-Cadena, Nina Dumauthioz, Giulia Vanoni, M. Kreutzfeldt, T. Wyss, L. Michalik, R. Loyon, A. Ianaro, Ping-Chih Ho, C. Borg, M. Kopf, D. Merkler, P. Krebs, P. Romero, S. Trabanelli, C. Jandus   +16 more
semanticscholar   +1 more source

The Pleiotropic Immunomodulatory Functions of IL-33 and Its Implications in Tumor Immunity

Frontiers in Immunology, 2018
Interleukin-33 (IL-33) is a IL-1 family member of cytokines exerting pleiotropic activities. In the steady-state, IL-33 is expressed in the nucleus of epithelial, endothelial, and fibroblast-like cells acting as a nuclear protein.
Claudia Afferni, Carla Buccione, Sara Andreone, Maria Rosaria Galdiero, Maria Rosaria Galdiero, Gilda Varricchi, Gilda Varricchi, Gianni Marone, Gianni Marone, Gianni Marone, Fabrizio Mattei, Giovanna Schiavoni   +11 more
doaj   +1 more source

Serum IL-5, POSTN and IL-33 levels in chronic rhinosinusitis with nasal polyposis correlate with clinical severity

BMC Immunology, 2022
Background Chronic rhinosinusitis (CRS) is a group of heterogeneous diseases characterized by epithelial inflammation and tissue eosinophilic infiltration.
Hanna Zielińska-Bliźniewska, Milena Paprocka-Zjawiona, Anna Merecz-Sadowska, Radosław Zajdel, Katarzyna Bliźniewska-Kowalska, Katarzyna Malinowska   +5 more
doaj   +1 more source

Bacteriological and Immunological study of kidney failure patients infected with urinary tract infections [PDF]

E3S Web of Conferences, 2023
Urinary tract infections (UTIs) are one of the most common medical conditions in women and men. They are caused by bacteria that enter the urinary tract through the urethra or the skin around the genitals.
Mhana Shahrabanawah Mahdi Yasin, Aljanaby Ahmed Abduljabbar Jaloob   +1 more
doaj   +1 more source

Intelectin contributes to allergen-induced IL-25, IL-33, and TSLP expression and type 2 response in asthma and atopic dermatitis. [PDF]

, 2017
The epithelial and epidermal innate cytokines IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) have pivotal roles in the initiation of allergic inflammation in asthma and atopic dermatitis (AD).
Cheng, D, Di, H, Erle, DJ, Huo, X, Mo, Y, Shi, H, Xu, Y, Yi, L, Zhang, H, Zhang, K, Zhao, J, Zhen, G, Zou, Y   +12 more
core   +1 more source