Results 61 to 70 of about 1,110,432 (191)

HpARI protein secreted by a helminth parasite suppresses interleukin-33 [PDF]

, 2017
Infection by helminth parasites is associated with amelioration of allergic reactivity, but mechanistic insights into this association are lacking.
Alasdair C. Ivens, Andrea Gonzàlez-Cìscar, Andrea M. Kemter, Anne L. Astier, Baker, Bartemes, Berman, Bessa, Blein, Buck, Bønnelykke, Bønnelykke, Castanhinha, Cayrol, Chen, Christianson, Claire Errington, Coakley, Cohen, Danielle J. Smyth, de Castro, De Salvo, Dennis Hoving, Dinesh C. Soares, E. Suzanne Cohen, Francesco Vacca, Gautier, Henry J. McSorley, Hewitson, Hewitson, Holly Henderson, Howe, Hristova, Hung, Ian C. Scott, Jackson, James P. Hewitson, Johnston, Jordan, Jürgen Schwarze, Kara J. Filbey, Kirkitadze, Kouzaki, Lawrence, Leffler, Lefrançais, Lefrançais, Lefrançais, Letunic, Liew, Lovell, Maizels, Maizels, Makou, Martin Wear, Matilda Toivakka, McSorley, McSorley, McSorley, Megan Osbourn, Moffatt, Morgan, Neill, Prota, Rick M. Maizels, Robert, Saglani, Sali, Saravia, Schiering, Shen, Shimokawa, Simon, Sjöberg, Soares, Soares, Sonja Vermeren, Söding, Thierry le Bihan, Thompson, Tordesillas, Trouw, William A. Wallace, William F. Gregory, Yang   +84 more
core   +7 more sources

L'interleukine-33, un nouvel acteur de la réponse anti-tumorale dans un modèle murin de cancer du côlon [PDF]

, 2014
L'interleukine-33 (IL-33) est une cytokine nucléaire de la famille des interleukines-1. L'IL-33 est exprimée par de nombreux épithéliums en contact avec l'environnement et peut être libérée sous sa forme pleine taille lors de nécrose.
Mirey, Emilie
core  

IL-33 regulates cytokine production and neutrophil recruitment via the p38 MAPK-activated kinases MK2/3 [PDF]

, 2019
IL‐33 is an IL‐1‐related cytokine that can act as an alarmin when released from necrotic cells. Once released, it can target various immune cells including mast cells, innate lymphoid cells and T cells to elicit a Th2‐like immune response.
Adachi, Ali, Ananieva, Andrade, Arthur, Benjamin, Cayrol, Chang, Clement, Darragh, Drube, Drube, Elcombe, Enoksson, Enoksson, Filippo, Funakoshi-Tago, Galloway, Gopfert, Helft, Hitti, Ho, Hochdorfer, Hodson, Huang, Hyatt, Iikura, Junttila, Kotlyarov, Kroeger, Liew, Lohning, Luthi, MacKenzie, Maitra, Marchese, Martin, McCoy, McDonald, McGuire, McGuire, Mjosberg, Molofsky, Monticelli, Moritz, Moulin, Naqvi, Neininger, Ottonello, Patial, Petri, Pozuelo, Qiu, Ronkina, Ronkina, Ross, Sanduja, Schiering, Schmidlin, Schmitz, Soukup, Stokoe, Sutavani, Suzuki, Swamydas, Taylor, Tung, Wiggin, Xiao, Xu, Zaru   +70 more
core   +2 more sources

The Relationship between the Genetic Polymorphisms of Interleukin-33 (IL-33) and Interleukin-1 Receptor-Like 1 (IL1R1) with the Levels of Interleukin-33 in Patients with Asthma and Multiple Sclerosis

مجله دانشکده پزشکی اصفهان, 2016
Background: Recent evidence suggests that the interleukin-33/interleukin-1 receptor-like 1 (IL-33/IL1RL1) axis plays a critical role in autoimmune and inflammatory disorders; however, its mechanistic role in these diseases has not been clearly defined ...
Maryam Ahmadi, Nahid Eskandari, Fereshteh Ale-Sahebfosoul, Mansour Salehi, Ramin Ghasemi   +4 more
doaj  

Mast cell responses to danger signals [PDF]

, 2012
Detecting and responding to danger is a paramount function of the immune system. Compounds heralding danger can be divided into two groups: exogenous and endogenous danger signals.
Enoksson, Mattias
core   +1 more source

Intravenously delivered graphene nanosheets and multiwalled carbon nanotubes induce site-specific Th2 inflammatory responses via the IL-33/ST2 axis [PDF]

, 2013
Carbon-based nanomaterials (CBN), such as graphene nanosheets (GNS) and multiwalled carbon nanotubes (MWCNT), have been proposed for potential nanomedicine applications such as biomedical devices and carriers for drug delivery.
Brown, Jared M, NC DOCKS at East Carolina University, Podila, Ramakrishna, Rao, Apparao M, Shannahan, Jonathan H, Wang, Xiaojia   +5 more
core   +3 more sources

The role and mechanism of IL-33 in gout [PDF]

, 2016
摘要 研究目的：以MSU诱导的小鼠实验性急性痛风为痛风研究模型，来探讨IL-33在急性痛风中的作用及其机制。 研究方法和结果： 1.重组小鼠IL-33的原核表达以及纯化 GST-IL-33融合蛋白经过原核表达、纯化，去除GST标签等步骤，获得了较高纯度的的mrIL-33。 2.对急性痛风患者血清中IL-33的研究 通过收集临床急性痛风患者41例（男39例，女2例）年龄26～91岁，平均58.3岁和44例年龄、性别与之匹配的健康志愿者的血清标本，检测血清中IL-33的含量。结果显示急性痛风患者血清中IL ...
苏群
core  

Serum soluble ST2 is associated with ER-positive breast cancer [PDF]

, 2014
BACKGROUND: ST2, a member of the interleukin (IL)-1receptor family, regulates Th1/Th2 immune responses in autoimmune and inflammatory conditions.
Cai-gang Liu, Da-peng Lu, Feng Jin, Lu-tian Yao, Wei Ma, Xiang-yu Zhou, Yun-fei Wu   +6 more
core   +1 more source

Novel Immunomodulatory Cytokine Regulates Inflammation, Diabetes, and Obesity to Protect From Diabetic Nephropathy

Frontiers in Pharmacology, 2019
Obesity-linked (type 2) diabetic nephropathy (T2DN) has become the largest contributor to morbidity and mortality in the modern world. Recent evidences suggest that inflammation may contribute to the pathogenesis of T2DN and T-regulatory cells (Treg) are
Vikram Sabapathy, Marta E. Stremska, Saleh Mohammad, Rebecca L. Corey, Poonam R. Sharma, Rahul Sharma   +5 more
doaj   +1 more source

Long-term IL-33-producing epithelial progenitor cells in chronic obstructive lung disease [PDF]

, 2013
Chronic obstructive lung disease is characterized by persistent abnormalities in epithelial and immune cell function that are driven, at least in part, by infection. Analysis of parainfluenza virus infection in mice revealed an unexpected role for innate
Anand C. Patel, Benjamini, Byers, Byers, Derek E. Byers, Dunning, Eugene Agapov, Evans, G. Alexander Patterson, Geoffrey Dang-Vu, Jean-Philippe Girard, Jennifer Alexander-Brett, Kangyun Wu, Karimi-Busheri, Kuyper, Michael J. Holtzman, Miniño, Richard A. Pierce, Rickel, Smyth, Steven L. Brody, Thaddeus S. Stappenbeck, Xiaohua Jin, Yael Alevy, Ying, Yingjian You   +25 more
core   +2 more sources