Results 71 to 80 of about 1,110,432 (191)

IL-33 and IL-3 synergistically induce CD25 expression on human basophils without functional IL-2 signaling: a potential marker of severe COVID-19

Frontiers in Immunology
CD25 (IL-2 receptor alpha chain) is a key component of the high-affinity receptor for the IL-2 cytokine and regulates the proliferation, survival, and differentiation of immune cells.
Sruthi Vijaya Retnakumar, Suraj Chandrabhan Singh, Camille Chauvin, Jagadeesh Bayry, Jagadeesh Bayry   +4 more
doaj   +1 more source

IL-33 Induces Paneth Cell Production of EGF and Soluble ST2, Regulating Epithelial Regeneration after Intestinal Injury [PDF]

, 2023
Marco Calafiore, Ya–Yuan Fu, Paola Vinci, Viktor Arnhold, Winston Chang, Suze A. Jansen, Anastasiya Egorova, Shuichiro Takashima, Jason Kuttiyara, Takahiro Ito, Jonathan S. Serody, Susumu Nakae, Hēth Turnquist, Johan H. van Es, Hans Clevers, Caroline A. Lindemans, Bruce R. Blazar, Alan M. Hanash   +17 more
openalex   +1 more source

IL1RAP Expression in Human Atherosclerosis: A Target of Novel Antibodies to Reduce Vascular Inflammation and Adhesion

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Blockade of IL1RAP (interleukin 1 receptor associated protein) was recently shown to reduce atherosclerosis in mice, but the effect on human vascular cells is largely unknown.
Madelene Lindkvist, Anna Göthlin Eremo, Geena Varghese Paramel, Sheikh Anisul Haque, Camilla Rydberg Millrud, Sara Rattik, Caitríona Grönberg, David Liberg, Allan Sirsjö, Karin Fransén   +9 more
doaj   +1 more source

The Participation of Interleukin Family 1 in the Development of the Inflammatory Response in Infectious Process. 4. Role of IL-1F11 (IL-33)

Zdorovʹe Rebenka, 2014
The review presents the characteristics of cytokine IL-1F11 (IL-33), its mechanisms of action and value in the development of inflammatory response.
A.Ye. Abaturov, A.P. Volosovets, Ye.I. Yulish   +2 more
doaj   +1 more source

Detrimental role of IL-33/ST2 pathway sustaining a chronic eosinophil-dependent Th2 inflammatory response, tissue damage and parasite burden during Toxocara canis infection in mice

, 2021
Thaís Leal-Silva, Flaviane Vieira-Santos, Luiza de Lima Silva Padrão, Lucas Kraemer Rocha, Pablo Hemanoel da Paixão Matias, Camila de Almeida Lopes, Ana Cristina Loiola Ruas, Isabella Carvalho De Azevedo, Denise Silva Nogueira, Milene Alvarenga Rachid, Marcelo Vidigal Caliari, Remo Castro Russo, Lilian Lacerda Bueno, Fabrício Marcus Silva Oliveira, Ricardo Toshio Fujiwara   +14 more
openalex   +1 more source

ILC2s chew the fat. [PDF]

, 2019
In this issue of JEM, Rana et al. (https://doi.org/10.1084/jem.20190689) report that adipose tissue multipotent stromal cells (MSCs) provide multifaceted support for adipose tissue-resident ILC2s through contact-mediated proliferation and IL-33-mediated ...
Locksley, Richard M, Ricardo-Gonzalez, Roberto R   +1 more
core   +1 more source

The TAK1→IKKβ→TPL2→MKK1/MKK2 Signaling Cascade Regulates IL-33 Expression in Cystic Fibrosis Airway Epithelial Cells Following Infection by Pseudomonas aeruginosa [PDF]

, 2016
In cystic fibrosis (CF), chronic respiratory infections result in an exaggerated and uncontrolled inflammatory response that ultimately lead to a decrease in pulmonary function.
Raquel Farias, Simon Rousseau
core   +2 more sources

Association of IL‐33 in modeling type‐2 airway inflammation and pulmonary emphysema in mice

Immunity, Inflammation and Disease
We developed pulmonary emphysema and a type 2 airway inflammation overlap mouse model. The bronchoalveolar lavage (BAL) interleukin 13 (IL‐13), IL‐4, and IL‐5 levels in the overlap model were higher than in the pulmonary emphysema model and lower than in
Chika Miyaoka, Masato Watanabe, Keitaro Nakamoto, Yuki Yoshida, Aya Hirata, Jumpei Aso, Hiroki Nunokawa, Manabu Ishida, Koujiro Honda, Saori Takata, Takeshi Saraya, Haruyuki Ishii   +11 more
doaj   +1 more source

MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation. [PDF]

, 2017
MicroRNAs (miRNAs) exert powerful effects on immunity through coordinate regulation of multiple target genes in a wide variety of cells. Type 2 innate lymphoid cells (ILC2s) are tissue sentinel mediators of allergic inflammation.
Ansel, K Mark, Baumjohann, Dirk, Happ, Hannah C, Locksley, Richard M, Pua, Heather H, Schneider, Christoph, Singh, Priti B, von Moltke, Jakob   +7 more
core   +2 more sources

Sexual maturation protects against development of lung inflammation through estrogen. [PDF]

, 2016
Increasing levels of estrogen and progesterone are suggested to play a role in the gender switch in asthma prevalence during puberty. We investigated whether the process of sexual maturation in mice affects the development of lung inflammation in ...
Boorsma, Carian E, Draijer, Christina, Greene, Catherine M, Hylkema, Machteld N, Klok, Pieter A, Melgert, Barbro N, Postma, Dirkje S, Robbe, Patricia, Timens, Wim   +8 more
core   +1 more source