Results 131 to 140 of about 2,610,317 (379)
VSIG4 mediates transcriptional inhibition of Nlrp3 and Il-1β in macrophages
Science Advances, 2019 VSIG4 controls inflammation through MS4A6D-mediated transcriptional inhibition of Nlrp3 and Il-1β in macrophages. Hyperactivation of the NLRP3 inflammasome contributes to the pathogenesis of multiple diseases, but the mechanisms underlying ...
Xiaoyong Huang +11 more
semanticscholar +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Effect of Perceived Stress on Cytokine Production in Healthy College Students [PDF]
, 2015 Chronic psychological stress impairs antibody synthesis following influenza vaccination. Chronic stress also increases circulating levels of proinflammatory cytokines and glucocorticoids in elders and caregivers, which can impair antibody synthesis.
McCarthy, Donna O. +3 more
core +1 more source
Review of: "Sputum Interleukin-32 in childhood asthma: correlation with IL-1β" [PDF]
, 2023 Lin Lin
openalex +1 more source
The Role of NLRP3 and IL-1β in the Pathogenesis of Inflammatory Bowel Disease
Frontiers in Immunology, 2018 It is logical to assume that a major pro-inflammatory mechanism, i.e., the NLRP3 inflammasome would play a prominent role in the pathogenesis of the Inflammatory Bowel Disease (IBD) in humans.
Liming Mao +3 more
semanticscholar +1 more source
, 2017 The overview of microarray analysis work flow (Figure S1) and the list of human housekeeping genes matching with gene array in microarray BeadChip (Table S1). (DOCX 32Â kb)
Onusa Thamsermsang +3 more
openaire +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1β [PDF]
, 2013 Introduction: Arthritic diseases are characterized by the degradation of collagenous and noncollagenous extracellular matrix (ECM) components in articular cartilage.
Allaway, David +5 more
core +2 more sources
, 2017 The list of significant gene alterations; up-regulation (Table S1) and down-regulation (Table S2) (DOCX 26Â kb)
Onusa Thamsermsang +3 more
openaire +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source