Results 21 to 30 of about 2,339,252 (343)

Autophagy Mediates Interleukin-1β Secretion in Human Neutrophils

Frontiers in Immunology, 2018
Interleukin-1β (IL-1β), a major pro-inflammatory cytokine, is a leaderless cytosolic protein whose secretion does not follow the classical endoplasmic reticulum-to-Golgi pathway, and for which a canonical mechanism of secretion remains to be established.
Leonardo Iula, Irene A. Keitelman, Florencia Sabbione, Federico Fuentes, Mauricio Guzman, Jeremías Gastón Galletti, Pehuén Pereyra Gerber, Matías Ostrowski, Jorge R. Geffner, Jorge R. Geffner, Carolina C. Jancic, Carolina C. Jancic, Analía S. Trevani, Analía S. Trevani   +13 more
doaj   +1 more source

IL-1β, IL-6, TNF- α and CRP in Elderly Patients with Depression or Alzheimer’s disease: Systematic Review and Meta-Analysis

Scientific Reports, 2018
We carried out systematic review and meta-analysis to evaluate whether peripheral levels of pro-inflammatory markers including Interleukin-1 beta (IL-1β), Interleukin-6 (IL-6), Tumor Necrosis Factor-α (TNF- α) and C-Reactive Protein (CRP) are ...
Ada Ng, W. Tam, M. Zhang, Cyrus S. H. Ho, S. F. Husain, R. McIntyre, R. Ho   +6 more
semanticscholar   +1 more source

Targeting IL-1β in the Treatment of Atherosclerosis

Frontiers in Immunology, 2020
The role of inflammation in atherosclerosis has been recognized several decades ago and existing treatments provide benefits in part through non-specific anti-inflammatory actions.
Wuqian Mai, Yuhua Liao
semanticscholar   +1 more source

Interleukin-1β-Induced Promatrilysin Expression is Mediated by NFκB-Regulated Synthesis of Interleukin-6 in the Prostate Carcinoma Cell Line, LNCaP

Neoplasia: An International Journal for Oncology Research, 2001
Previously, our laboratory showed that interleukin-1β (IL-1β) secreted by lipopolysaccharide-activated monocytes induces promatrilysin expression in the prostate carcinoma cell line, LNCaP.
Mimi Suzanne Maliner-Stratton, Russell D. Klein, Thirupandiyur S. Udayakumar, Raymond B. Nagle, George Timothy Bowden   +4 more
doaj   +1 more source

Zinc depletion regulates the processing and secretion of IL-1β [PDF]

Cell Death & Disease, 2014
AbstractSterile inflammation contributes to many common and serious human diseases. The pro-inflammatory cytokine interleukin-1β (IL-1β) drives sterile inflammatory responses and is thus a very attractive therapeutic target. Activation of IL-1β in sterile diseases commonly requires an intracellular multi-protein complex called the NLRP3 (NACHT, LRR ...
Pedrosa Mendes, Pedro, Summersgill, H., England, H., Lopez-Castejon, G., Lawrence, C. B., Luheshi, N. M., Pahle, J., Mendes, P., Brough, D.   +8 more
openaire   +4 more sources

The expression of TNF-α, IL-1β, and IL-10 in the diabetes mellitus condition induced by the combination of spirulina and chitosan

Bali Medical Journal, 2020
Background: Rapid wound healing is needed after tooth extraction treatment so that prosthodontics treatment can be done immediately. However, systemic diseases, such as diabetes mellitus, can inhibit the wound healing process. The state of hyperglycemia in people with diabetes mellitus can interfere with the function of macrophages and neutrophils ...
Nike Hendrijantini, -, Ratri Maya Sitalaksmi, -, Muhammad Dimas Aditya Ari, -, Tiffany Josephine Hidayat, -, Prisca Agustina Nurcahyani Putri, -, Daniel Sukandar, -   +5 more
openaire   +2 more sources

The Correlation of SKA2 with Cortisol, IL-1β and Anxiety in Pregnant Women with the Risk of Preterm Delivery [PDF]

Psychiatry Investigation, 2020
Objective The association between preterm birth (PTB), Spindle and Kinetochore Associated Complex Subunit 2 gene (<i>SKA2</i>), cortisol and anxiety have been shown, but in this study, we aimed to clarify whether the expression of the <i>SKA2</i> gene plays a role in interleukin1β (IL-1β) level since increasing level of IL-1β is
Ijabi, J., Afrisham, R., Moradi-Sardareh, H., Roozehdar, P., Seifi, F., Ijabi, R.   +5 more
openaire   +2 more sources

The In Situ Expression of IL-6 and IL-1? in breast cancer patients

Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512), 2017
Breast cancer is the second most common cancer in women world. Multiple Cytokines appear to have a dominant role in human breast cancer formation. Estimation of the in situ expression of  IL-6 and IL-1β in breast cancer patients. A sixty patients with breast cancer BC were divided into two clinical subgroups, (30) with malignant breast cancer MBC and (
Amal H. Salman, Mayada N. Iqbal, Wasan A. Bakir   +2 more
openaire   +3 more sources

Evaluation of IL-1β and TNF-α expression and periodontitis under the influence of orthodontic appliances with minocycline

Cellular and Molecular Biology, 2020
The current experiment was carried out to observe and analyze the effects of three orthodontic appliances combined with minocycline on periodontitis and inflammatory factors of gingival crevicular fluid. the patients included in this study were 180 patients with dental crowding treated in our hospital.
Weican Chen, Hongwei Hui, Suqing Qi, Jingjing Zhang, Lin Liu   +4 more
openaire   +4 more sources

Modulation of human polymorphonuclear leukocyte chemotaxis and superoxide anion production byPseudomonas aeruginosaexoproducts, IL-1β and piroxicam [PDF]

FEMS Immunology & Medical Microbiology, 1995
Whereas addition of 200 ng ml-1 exotoxin A (exoA) did not modify PMNL chemotaxis, 20 U ml-1 human recombinant interleukin-1 beta (hrIL-1 beta) primed polymorphonuclear leukocytes (PMNL) for migration towards Pseudomonas aeruginosa peptide chemotactins (PAPCs).
P. A. Fontán, Fernanda R. Buzzola, Claudia R. Amura, Daniel O. Sordelli   +3 more
openaire   +3 more sources