Results 61 to 70 of about 2,339,252 (343)

The Correlation b etween IL - 1β and IL - 10 Levels in Estimating t he Risk of Febrile Seizures

Journal of Tropical Life Science, 2014
Febrile seizures are the most-common form of seizures in children with fever and evidence from clinical and experimental studies suggests the potential role of immune generated products in their genesis.
Gunawan A, Muid M, Sujuti H, Barlianto W, Subandiyah K   +4 more
doaj  

Species-specific IL-1β is an inflammatory sensor of Seneca Valley Virus 3C Protease.

PLoS Pathogens
Inflammasomes play pivotal roles in inflammation by processing and promoting the secretion of IL-1β. Caspase-1 is involved in the maturation of IL-1β and IL-18, while human caspase-4 specifically processes IL-18.
Xiangyu Huang, Zhenchao Zhao, Cheng Zhu, Lvye Chai, Ya Yan, Ye Yuan, Lei Wu, Minjie Li, Xiaohan Jiang, Haiwei Wang, Zheng Liu, Pingwei Li, Xin Li   +12 more
doaj   +1 more source

Interference of Interleukin-1β Mediated by Lentivirus Promotes Functional Recovery of Spinal Cord Contusion Injury in Rats via the PI3K/AKT1 Signaling Pathway

Mediators of Inflammation, 2022
Purpose. Inflammation and apoptosis after spinal cord contusion (SCC) are important causes of irreversible spinal cord injury. Interleukin-1β (IL-1β) is a key inflammatory factor that promotes the aggravation of spinal cord contusion.
Jun-Feng Cao, Xi Hu, Li Xiong, Mei Wu, Xingyu Yang, Chaochao Wang, Shengyan Chen, Hengxiang Xu, Huanyu Chen, Xuntai Ma, Yongjie Mi, Xiao Zhang   +11 more
doaj   +1 more source

Alteration of dopamine, homovanillic acid (HVA) with interleukine-1β (IL-1β) and tumor necrosis factor-α (TNF-α) in cerebral palsy [PDF]

Biodiversitas Journal of Biological Diversity, 1970
Now, diagnosis of cerebral palsy base only on clinical finding without involve the alteration of the neurochemistry cause by cerebral hypoxic, although cerebral palsy is a syndrome cause by cerebral hypoxic; so, the accuracy diagnosis of this disease is very low.
openaire   +2 more sources

Inhibition of uric acid or IL‐1β ameliorates respiratory syncytial virus immunopathology and development of asthma

Allergy, 2020
AbstractBackgroundRespiratory syncytial virus (RSV) affects most infants early in life and is associated with increased asthma risk. The specific mechanism remains unknown.ObjectiveTo investigate the role of uric acid (UA) and IL‐1β in RSV immunopathology and asthma predisposition.MethodsTracheal aspirates from human infants with and without RSV were ...
Charles F. Schuler, Carrie‐Anne Malinczak, Shannon K. K. Best, Susan B. Morris, Andrew J. Rasky, Catherine Ptaschinski, Nicholas W. Lukacs, Wendy Fonseca   +7 more
openaire   +5 more sources

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Producción de citoquinas proinflamatorias durante los estadios tempranos de la infección experimental por Paracoccidioides brasiliensis

Iatreia, 2001
La paracoccidioidomicosis (PCM) es una micosis sistémica restringida a América Latina y producida por la inhalación de las conidias del hongo dimórfico Paracoccidioides brasilienis (Pb) (1).
Luz Elena Cano, Angela Restrepo, Blanca Ortiz, Jorge Sahaza, Angel González   +4 more
doaj  

Salmonella manipulates the host to drive pathogenicity via induction of interleukin 1β.

PLoS Biology
Acute gastrointestinal infection with intracellular pathogens like Salmonella Typhimurium triggers the release of the proinflammatory cytokine interleukin 1β (IL-1β).
Mor Zigdon, Jasmin Sawaed, Lilach Zelik, Dana Binyamin, Shira Ben-Simon, Nofar Asulin, Rachel Levin, Sonia Modilevsky, Maria Naama, Shahar Telpaz, Elad Rubin, Aya Awad, Wisal Sawaed, Sarina Harshuk-Shabso, Meital Nuriel-Ohayon, Mathumathi Krishnamohan, Michal Werbner, Omry Koren, Sebastian E Winter, Ron N Apte, Elena Voronov, Shai Bel   +21 more
doaj   +1 more source

Glibenclamide inhibits NLRP3 inflammasome-mediated IL-1β secretion in human trophoblasts

Journal of Pharmacological Sciences, 2017
Infection-associated pregnancy complications cause premature delivery. Caspase-1 is involved in the maturation of interleukin (IL)-1β, which is activated by the NLRP3 inflammasome. To characterize the significance of the NLRP3 inflammasome pathway in the placenta, the effects of activators and inhibitors on NLRP3-related molecules were examined using ...
Mikihiro Yoshie, Gen Ishikawa, Wakana Ohneda, Eiichi Tachikawa, Akihito Nakai, Kazuhiro Tamura, Toshiyuki Takeshita   +6 more
openaire   +4 more sources

The inflammatory molecules IL-1β and HMGB1 can rapidly enhance focal seizure generation in a brain slice model of temporal lobe epilepsy [PDF]

Frontiers in Cellular Neuroscience, 2014
Epilepsy is a neurological disorder characterized by a hyperexcitable brain tissue and unpredictable seizures, i.e., aberrant firing discharges in large neuronal populations. It is well established that proinflammatory cytokines, in addition to their canonical involvement in the immune response, have a crucial role in the mechanism of seizure ...
Chiavegato, Angela, Zurolo, Emanuele, Losi, Gabriele, Aronica, Eleonora, Carmignoto, Giorgio   +4 more
openaire   +4 more sources