Results 11 to 20 of about 1,850,686 (245)

IL-1 family nomenclature [PDF]

open access: yesNature Immunology, 2010
To the Editor: Newly cloned interleukin 1 (IL-1) family members1–3 were originally given an IL-1 family (IL-1F) designation4, but as functions have now been elucidated for several of these5,6, we propose that each now be assigned an individual interleukin designation.
Dinarello, C.A.   +34 more
openaire   +6 more sources

Study regarding the use of salivary 8-hydroxideoxyguanosine and Interleukin-1 gene polymorphism - as potential biomarkers in the diagnosis of aggressive periodontitis

open access: yesRomanian Journal of Laboratory Medicine, 2013
Scopul acestui studiu este de a explora posibilitatea de a folosi 8-hidroxideoxiguanozina salivara (8-OHdG) şi polimorfismul genei interleukinei-1 (IL-1) salivare în diagnosticul pacienţilor cu boală parodontală agresivă.
Badea Victoria   +5 more
doaj   +1 more source

Actions of Prostaglandins on Human Nucleus Pulposus Metabolism Inferred by Cyclooxygenase 2 Inhibition of Cytokine Activated Cells [PDF]

open access: yesNeurospine, 2020
Objective Low back pain is frequently treated with nonsteroidal anti-inflammatory drugs (NSAIDs), but little is known about intervertebral disc metabolism of the prostaglandins that are diminished by these drugs.
Nam Vo   +5 more
doaj   +1 more source

Раціоналізація підходів до ведення епізіотомної рани

open access: yesУкраїнський журнал Здоров'я жінки, 2022
Епізіотомія - це хірургічна маніпуляція, що стала однією з найчастіших хірургічних процедур у світі. За рекомендаціями Всесвітньої організації охорони здоров’я, загальна частота епізіотомій не повинна перевищувати 10% вагінальних пологів.
M.B. Liashko, D.O. Govsieiev
doaj   +1 more source

Effects of IL‐1 receptor accessory protein on IL‐1 binding [PDF]

open access: yesFEBS Letters, 1998
Interleukin‐1 (IL‐1) is an important pro‐inflammatory cytokine that exerts its diverse biological functions by binding to a receptor complex consisting of two transmembrane proteins, type I IL‐1 receptor (IL‐1RI) and IL‐1 receptor accessory protein (IL‐1RAcP).
Wesche, H., Resch, K., Martin, M.U.
openaire   +2 more sources

The role of interleukin genes in the course of depression

open access: yesOpen Medicine, 2016
Research studies conducted in recent years have confirmed that in the absence of medical illnesses, depressive disorders are associated with upregulation of many inflammatory cytokines such as tumor necrosis factor-aplha (TNF-α), interleukin-1 and 6 (IL ...
Talarowska Monika   +2 more
doaj   +1 more source

The Epistatic Interrelationships of IL-1, IL-1 Receptor Antagonist, and the Type I IL-1 Receptor [PDF]

open access: yesThe Journal of Immunology, 2002
Abstract Mice lacking the gene for the IL-1R antagonist (IL-1ra) show abnormal development and homeostasis as well as altered responses to infectious and inflammatory stimuli. A reduction in the level of IL-1 signaling, either by deletion of the receptor or increased expression of IL-1ra, does not affect development or homeostasis, but ...
Vera M, Irikura   +2 more
openaire   +2 more sources

A Brief History of IL-1 and IL-1 Ra in Rheumatology [PDF]

open access: yesFrontiers in Pharmacology, 2017
The history of what, in 1979, was called interleukin-1 (IL-1), orchestrator of leukocyte inter-communication, began many years before then, initially by the observation of fever induction via the endogenous pyrogen (EP) (1974) and then in rheumatology on the role in tissue destruction in rheumatoid diseases via the induction of collagenase and PGE2 in ...
DAYER, JEAN-MICHEL   +2 more
openaire   +4 more sources

Inflammatory and Anti-Inflammatory Parameters in PCOS Patients Depending on Body Mass Index: A Case-Control Study

open access: yesBiomedicines, 2023
Background: it has been suggested that chronic low-grade inflammation plays an important role in the pathogenesis of polycystic ovary syndrome (PCOS).
Elena Vasyukova   +8 more
doaj   +1 more source

ROLE OF IL-1 AND LIPID PEROXIDATION PRODUCTS IN PATHOGENESIS OF ACUTE PANCREATITIS

open access: yesМедицинская иммунология, 2014
. The review article presents data concerning pathogenetic mechanisms of acute pancreatitis development and poly-organ insufficiency. It was shown IL-1 is among important factors that may determine a severity degree of pancreatitis.
A. N. Plekhanov   +2 more
doaj   +1 more source

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