Results 11 to 20 of about 1,850,686 (245)
IL-1 family nomenclature [PDF]
To the Editor: Newly cloned interleukin 1 (IL-1) family members1–3 were originally given an IL-1 family (IL-1F) designation4, but as functions have now been elucidated for several of these5,6, we propose that each now be assigned an individual interleukin designation.
Dinarello, C.A. +34 more
openaire +6 more sources
Scopul acestui studiu este de a explora posibilitatea de a folosi 8-hidroxideoxiguanozina salivara (8-OHdG) şi polimorfismul genei interleukinei-1 (IL-1) salivare în diagnosticul pacienţilor cu boală parodontală agresivă.
Badea Victoria +5 more
doaj +1 more source
Actions of Prostaglandins on Human Nucleus Pulposus Metabolism Inferred by Cyclooxygenase 2 Inhibition of Cytokine Activated Cells [PDF]
Objective Low back pain is frequently treated with nonsteroidal anti-inflammatory drugs (NSAIDs), but little is known about intervertebral disc metabolism of the prostaglandins that are diminished by these drugs.
Nam Vo +5 more
doaj +1 more source
Раціоналізація підходів до ведення епізіотомної рани
Епізіотомія - це хірургічна маніпуляція, що стала однією з найчастіших хірургічних процедур у світі. За рекомендаціями Всесвітньої організації охорони здоров’я, загальна частота епізіотомій не повинна перевищувати 10% вагінальних пологів.
M.B. Liashko, D.O. Govsieiev
doaj +1 more source
Effects of IL‐1 receptor accessory protein on IL‐1 binding [PDF]
Interleukin‐1 (IL‐1) is an important pro‐inflammatory cytokine that exerts its diverse biological functions by binding to a receptor complex consisting of two transmembrane proteins, type I IL‐1 receptor (IL‐1RI) and IL‐1 receptor accessory protein (IL‐1RAcP).
Wesche, H., Resch, K., Martin, M.U.
openaire +2 more sources
The role of interleukin genes in the course of depression
Research studies conducted in recent years have confirmed that in the absence of medical illnesses, depressive disorders are associated with upregulation of many inflammatory cytokines such as tumor necrosis factor-aplha (TNF-α), interleukin-1 and 6 (IL ...
Talarowska Monika +2 more
doaj +1 more source
The Epistatic Interrelationships of IL-1, IL-1 Receptor Antagonist, and the Type I IL-1 Receptor [PDF]
Abstract Mice lacking the gene for the IL-1R antagonist (IL-1ra) show abnormal development and homeostasis as well as altered responses to infectious and inflammatory stimuli. A reduction in the level of IL-1 signaling, either by deletion of the receptor or increased expression of IL-1ra, does not affect development or homeostasis, but ...
Vera M, Irikura +2 more
openaire +2 more sources
A Brief History of IL-1 and IL-1 Ra in Rheumatology [PDF]
The history of what, in 1979, was called interleukin-1 (IL-1), orchestrator of leukocyte inter-communication, began many years before then, initially by the observation of fever induction via the endogenous pyrogen (EP) (1974) and then in rheumatology on the role in tissue destruction in rheumatoid diseases via the induction of collagenase and PGE2 in ...
DAYER, JEAN-MICHEL +2 more
openaire +4 more sources
Background: it has been suggested that chronic low-grade inflammation plays an important role in the pathogenesis of polycystic ovary syndrome (PCOS).
Elena Vasyukova +8 more
doaj +1 more source
ROLE OF IL-1 AND LIPID PEROXIDATION PRODUCTS IN PATHOGENESIS OF ACUTE PANCREATITIS
. The review article presents data concerning pathogenetic mechanisms of acute pancreatitis development and poly-organ insufficiency. It was shown IL-1 is among important factors that may determine a severity degree of pancreatitis.
A. N. Plekhanov +2 more
doaj +1 more source

