Results 31 to 40 of about 34,732,115 (289)

Molecular mechanisms of IL-18BP regulation in DLD-1 cells: pivotal direct action of the STAT1/GAS axis on the promoter level [PDF]

, 2008
Interleukin (IL)-18, formerly known as interferon (IFN)-γ-inducing factor, is a crucial mediator of host defence and inflammation. Control of IL-18 bioactivity by its endogenous antagonist IL-18 binding protein (IL-18BP) is a major objective of ...
Jens Paulukat, Heiko Mühl, Malte Bachmann, Josef Pfeilschifter, Pfeilschifter, Josef, Bachmann, Malte, Mühl, Heiko, Paulukat, Jens   +7 more
core   +1 more source

ROLE OF IL-1 AND LIPID PEROXIDATION PRODUCTS IN PATHOGENESIS OF ACUTE PANCREATITIS

Медицинская иммунология, 2014
. The review article presents data concerning pathogenetic mechanisms of acute pancreatitis development and poly-organ insufficiency. It was shown IL-1 is among important factors that may determine a severity degree of pancreatitis.
A. N. Plekhanov, D. I. Reshetnikov, A. I. Tovarshinov   +2 more
doaj   +1 more source

Inflammatory and Anti-Inflammatory Parameters in PCOS Patients Depending on Body Mass Index: A Case-Control Study

Biomedicines, 2023
Background: it has been suggested that chronic low-grade inflammation plays an important role in the pathogenesis of polycystic ovary syndrome (PCOS).
Elena Vasyukova, Ekaterina Zaikova, Olga Kalinina, Inga Gorelova, Irina Pyanova, Elena Bogatyreva, Elena Vasilieva, Elena Grineva, Polina Popova   +8 more
doaj   +1 more source

IL-27 regulates IL-18 binding protein in skin resident cells [PDF]

, 2012
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M, Miriam Wittmann, Werfel, Thomas, Bachmann, M, Doble, Rosella, Muehl, H, Thomas Werfel, Doble Rosella, Pfeilschifter, Josef (Prof. Dr.), Doble, R, Heiko Mühl, Mühl Heiko, Malte Bachmann, Wittmann Miriam, Pfeilschifter, J, Wittmann, Miriam, Bachmann Malte, Werfel, T, Josef Pfeilschifter, Werfel Thomas, Bachmann, Malte, Mühl, Heiko, Rosella Doble, Pfeilschifter Josef   +23 more
core   +2 more sources

Association between vitamin D receptor gene polymorphisms, inflammatory cytokines (IL-1, IL-6, and IL-10), and fracture healing in sports-related injuries [PDF]

Journal of Medical Biochemistry
Background: In this study, we analysed the correlation between polymorphisms in the Vitamin D receptors (VDR) gene at the Apa I and FoK I loci and sports-related fractures (SRF).
Wang Dan
doaj   +1 more source

Cytoplasmic tail of IL-13Ralpha2 regulates IL-4 signal transduction

, 2009
IL (interleukin)-4 and IL-13 are key cytokines in the pathogenesis of allergic inflammatory disease. IL-4 and IL-13 share many functional properties as a result of their utilization of a common receptor complex comprising IL-13Ralpha1 (IL-13 receptor ...
Donna E. Davies, Holgate, Stephen T, Isabelle Kirby, Ida Karin Nordgren, Tavassoli, Ali, Davies, Donna E, Holloway, John W, Andrews, Allison-Lynn, Stephen T. Holgate, Nordgren, Ida Karin, John W. Holloway, Kirby, Isabelle, Allison-Lynn Andrews, Ali Tavassoli   +13 more
core   +1 more source

Effects of short- and long-term regular exercise on reproductive tissue in streptozotocin-induced diabetic male Wistar rats

Endocrine Regulations, 2018
Objective. Reproductive disorders are one of the complications of diabetes mellitus. Since conflicting results have been obtained from different studies, which examined serum levels of cytokines in patients with diabetes, and considering the fact that ...
Mogaddami Zahra, Sheikhzadeh Farzam, Hatami Homeira, Khojasteh Seyed Mahdi Banan, Khajehnasiri Nazli, Hemmati Ali Reza Ali, Dastranj Ali   +6 more
doaj   +1 more source

Application of anakinra in inflammatory dermatoses

Pifu-xingbing zhenliaoxue zazhi
Interleukin 1(IL-1) is an important cytokine, which is involved in the development of many inflammatory diseases. IL-1 inhibitors have become an effective approach in the treatment of these diseases.
Xiaomei YOU, Ganlin GU, Yanyun JIANG, Liangchun WANG   +3 more
doaj   +1 more source

SPECIFIC STAGE-DEPENDENT FEATURES OF CYTOKINE CASCADE IN THE PATIENTS WITH BRONCHIAL ASTHMA

Медицинская иммунология, 2014
. A study of leukocyte regulation system in patients with exacerbated bronchial asthma (BA) was performed by means of measuring spontaneous and induced production of certain cytokines (IL-4, IL-1b, IL-10 and IFNg) in whole blood, and drawing some ...
L. V. Ryabova, A. V. Zurochka
doaj   +1 more source

The Effect of D-Peptide-B and B.Bifidum Probiotic Lysate on the Expression of TNF-α and IL-1 Genes in AGS Cancer Cell Line Compared to Healthy HEK Cells [PDF]

پیاورد سلامت, 2023
Background and Aim: Today, natural compounds such as peptides and probiotics can be mentioned as a supplement to the treatment of diseases such as cancer.
Shima Derakhshan, Negar Yavari Tehrani Fard, Nahid Abotalbe, Maryam Naseroleslami   +3 more
doaj