Results 11 to 20 of about 1,896,687 (246)

Association between vitamin D receptor gene polymorphisms, inflammatory cytokines (IL-1, IL-6, and IL-10), and fracture healing in sports-related injuries [PDF]

Journal of Medical Biochemistry
Background: In this study, we analysed the correlation between polymorphisms in the Vitamin D receptors (VDR) gene at the Apa I and FoK I loci and sports-related fractures (SRF).
Wang Dan
doaj   +2 more sources

Low-level Laser Therapy and Changes in Salivary Proinflammatory Cytokines: A Systematic Review [PDF]

Journal of Health Sciences and Surveillance System, 2023
Background: The effect of laser on reducing inflammation has always been considered. The aim of this study was to evaluate the clinical studies on the effect of using low-power lasers on the production and activity of proinflammatory cytokines such as IL-
Fatemeh Baljani, Habib Khoshvaghti, Fatemeh Tavakoli, Vahid Fakhrzadeh, Hosein Eslami   +4 more
doaj   +1 more source

Anemia of inflammation in patients with colorectal cancer: Correlation with interleukin-1, interleukin-33 and galectin-1 [PDF]

Journal of Medical Biochemistry, 2022
Background: Patients with colorectal cancer (CRC) have anemia often present as a consequence of chronic bleeding from tumor. The exact role of lL-33, Galectin-l and IL-l in the pathological genesis of anemia in colorectal cancer patients has not been ...
Jocić Miodrag, Arsenijević Nebojša, Gajović Nevena, Jurišević Milena, Jovanović Ivan, Jovanović Milan, Zdravković Nataša, Marić Veljko, Jovanović Marina   +8 more
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Clinical and Genetic Characteristics, Target Therapy Results in Children with Traps Syndrome (on Clinical Surveillance Data)

Научно-практическая ревматология, 2021
The complexity of diagnosing and predicting the course of TNF-receptor-associated periodic syndrome TRAPS determines the importance of studying the dependence of clinical manifestations on the variant of genetic mutation and the presence of modifier ...
E. V. Antsiferova, T. V. Cherkashina, N. G. Wolf, I. Yu. Naumenko, E. A. Anikina, N. G. Kiseleva, N. Yu. Makarevskaya, T. E. Taranushenko, L. N. Antsiferova, E. Yu. Emelyanchik   +9 more
doaj   +1 more source

Improving cancer immunotherapy by targeting IL-1

OncoImmunology, 2021
Interleukin-1 (IL-1) is an inflammatory cytokine associated with tumor invasiveness and metastasis. We recently found that baseline IL-1 in melanomas promoted resistance to immunotherapy by creating an immunosuppressive tumor microenvironment and that IL-
Zhilan Xiao, Shubhra Singh, Manisha Singh   +2 more
doaj   +1 more source

Prediction of diacerein inhibition activity against interleukin-1 receptors through docking method and tracing of pharmacokinetic profiles and their toxicity [PDF]

Pharmaciana, 2020
IL-1 is one of the cytokines involved in joint diseases such as osteoarthritis. IL-1 plays a role in maintaining the balance of proteolytic proteins:MMPs and TIMPs inhibitors.
Frengki Frengki, Vivi Sofia, Deddi Prima Putra, Fatma Sri Wahyuni, Daan Khambri, Henni Vanda   +5 more
doaj   +1 more source

A Brief History of IL-1 and IL-1 Ra in Rheumatology [PDF]

Frontiers in Pharmacology, 2017
The history of what, in 1979, was called interleukin-1 (IL-1), orchestrator of leukocyte inter-communication, began many years before then, initially by the observation of fever induction via the endogenous pyrogen (EP) (1974) and then in rheumatology on the role in tissue destruction in rheumatoid diseases via the induction of collagenase and PGE2 in ...
DAYER, JEAN-MICHEL, OLIVIERO, FRANCESCA, PUNZI, LEONARDO   +2 more
openaire   +5 more sources

The Epistatic Interrelationships of IL-1, IL-1 Receptor Antagonist, and the Type I IL-1 Receptor [PDF]

The Journal of Immunology, 2002
Abstract Mice lacking the gene for the IL-1R antagonist (IL-1ra) show abnormal development and homeostasis as well as altered responses to infectious and inflammatory stimuli. A reduction in the level of IL-1 signaling, either by deletion of the receptor or increased expression of IL-1ra, does not affect development or homeostasis ...
Vera M, Irikura, Mouna, Lagraoui, David, Hirsh   +2 more
openaire   +2 more sources

Changes in cytokine profile with immunotherapy in viral warts using purified protein derivative, mumps measles rubella vaccine, and mycobacterium w vaccine

Indian Journal of Dermatology, 2021
Background: Immunotherapy for wart employs ability of immune system to recognize certain viral, bacterial, and fungal antigens in previously sensitized individual inducing Type IV delayed-type hypersensitivity reaction (up-regulated Th1 cytokines IL-1 ...
Amrita Sil, Sayantan Dasgupta, Somodyuti Chandra, Adrija Datta, Arini Banerjee, Nilay Kanti Das   +5 more
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Effects of IL‐1 receptor accessory protein on IL‐1 binding [PDF]

FEBS Letters, 1998
Interleukin‐1 (IL‐1) is an important pro‐inflammatory cytokine that exerts its diverse biological functions by binding to a receptor complex consisting of two transmembrane proteins, type I IL‐1 receptor (IL‐1RI) and IL‐1 receptor accessory protein (IL‐1RAcP).
Wesche, H., Resch, K., Martin, M.U.
openaire   +2 more sources