Results 61 to 70 of about 2,185,989 (294)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Evaluación de polimorfismos en los genes de TNF-alfa, TNF-beta e IL-1beta y sus variantes alélicas en una población colombiana de pacientes con sepsis

Iatreia, 2010
La sepsis se define como un síndrome de respuesta sistémica en presencia,  confirmada o sospechada de infección. Se manifiesta  con uno o varios marcadores de enfermedad general, inflamación, anormalidad hemodinámica, disfunción orgánica o falla de ...
Carolina Montoya Ruiz, Maira Alegandra Diosa Toro, Paula Andrea Velilla, Fabián Jaimes Barragán   +3 more
doaj  

Andrographolide relieved pathological pain generated by spared nerve injury model in mice

Pharmaceutical Biology, 2018
Context: Andrographolide (Andro), found in large quantities in Andrographis paniculata Nees (Acanthaceae), is anti-inflammatory, especially in the central nervous system (CNS) glia.
Huang-Chi Wang, Hsin-Sheng Tsay, Hui-Nung Shih, Yi-An Chen, Kai-Ming Chang, Dinesh Chandra Agrawal, Siendong Huang, Yi-Lo Lin, Meng-Jen Lee   +8 more
doaj   +1 more source

Interleukin-1 involved in Apoptosis of Beta-Thalassemia/Hemoglobin E Erythroid Progenitor Cells

Asian Journal of Medical Sciences, 2013
Objective: The major pathophysiological features of β-thalassemia are anemia and ineffective erythropoiesis. Ineffective erythropoiesis has been shown by an intense marrow erythroid hyperplasia and increased apoptosis during basophilic to orthochromatic ...
Umesh Prasad Gupta
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Effects of Hemiscorpius lepturus scorpion venom fractions on cytokine release in male rats [PDF]

مجله علوم پزشکی فیض (پیوسته)
Background and Aim: The secretion and activation of cytokines play a significant role in the pathogenesis of scorpion venom. This study aimed to investigate the effects of Hemiscorpius lepturus scorpion venom fractions on the release of IL-1, IL-6, and ...
Daniel Shaebannia, Mohammad Razi jalali, Ali Shahrirari, Hedieh Jafari, Masoumeh Ahmadi zadeh   +4 more
doaj  

Effect of Epigallocatechin Gallate on the Inflammatory Response in Mice (Mus musculus) Kidneys

Journal of Applied Veterinary Science and Technology
Background: Epigallocatechin gallate is the primary polyphenol constituent of green tea. It has the ability to inhibit the pathological processes caused by oxidants. However, in certain cases, the green tea diet is known to exert pro-oxidant effects.
Gegana Wimaldy Airlangga, Balqis Aina Fajriya, Andreas Bandang Hardian   +2 more
doaj   +1 more source

CYTOKINE GENE POLYMORPHISMS AS PREDICTORS OF CHRONIC PAIN SYNDROME IN ONCOLOGY

Сибирский онкологический журнал, 2017
The literature review on the role of cytokine gene polymorphisms in the development of chronic pain in cancer patients was presented using MedLine, PubMed, NEB elibrary.ru, WileyOnlineLibrary, WebofScience, OxfordUniversityPress and SAGEPremier databases
O. P. Bobrova, N. A. Shnayder, M. M. Petrova, K. S. Zyryanov, D. A. Sychev   +4 more
doaj   +1 more source

IL-1 regulates the IL-23 response to wheat gliadin, the etiologic agent of Celiac Disease [PDF]

, 2008
Celiac disease (CD) is an autoimmune disease prevalent in ~1% of the general population. CD is unique because both the major genetic (Human Leukocyte Antigen-DQ2/DQ8 alleles) and etiologic factors (dietary glutens) for susceptibility are known.
Alessio Fasano, Dean L. Mann, Kristina M. Harris   +2 more
core   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source