Results 121 to 130 of about 77,313,502 (292)

Cryo-EM structure of the IL-10 receptor complex provides a blueprint for ligand engineering. [PDF]

FEBS J, 2022
Saxton RA, Garcia KC.
europepmc   +1 more source

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source

Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients [PDF]

, 2011
Introduction: Systemic inflammation (e.g. following surgery) involves Toll-like receptor (TLR) signaling and leads to an endocrine stress response. This study aims to investigate a possible influence of TLR2 and TLR4 single nucleotide polymorphisms (SNPs)
Carsten Schwenke, Matthias Schott, Koch, Alexander, Stefan R Bornstein, Ralf R Schumann, Schott, Matthias, Lutz Hamann, Hamann, Lutz, Bornstein, Stefan R., Schwenke, Carsten, Alexander Koch, Muhammed Kurt, Zacharowski, Kai, Kai Zacharowski, Olaf Boehm, Schumann, Ralf R., Grotemeyer, Dirk, Kurt, Muhammed, Boehm, Olaf, Dirk Grotemeyer   +19 more
core   +1 more source

Identification of macrophage-inducible C-type lectin receptor stimulatory glycolipids from Lactiplantibacillus plantarum OLL2712 that induce interleukin-10 production in dendritic cells

Journal of Dairy Science
: Lactiplantibacillus plantarum OLL2712 is a lactic acid bacterium originally selected for its strong induction of IL-10 in innate immune cells. We recently discovered that IL-10 induction is mediated by the C-type lectin receptor, macrophage-inducible C-
T. Shimazu, R. Sakabe, K. Nakayama, S. Nanaumi, A. Nakajima, T. Toshimitsu, S. Yamasaki, T. Sashihara   +7 more
doaj   +1 more source

Mycobacterium tuberculosis Rv2145c Promotes Intracellular Survival by STAT3 and IL-10 Receptor Signaling. [PDF]

Front Immunol, 2021
Park HS, Back YW, Jang IT, Lee KI, Son YJ, Choi HG, Dang TB, Kim HJ.   +7 more
europepmc   +1 more source

IL-10/IL-10 receptor 1 pathway promotes the viability and collagen synthesis of pulmonary fibroblasts originated from interstitial pneumonia tissues. [PDF]

Exp Ther Med, 2022
Ye H, Pan J, Cai X, Yin Z, Li L, Gong E, Xu C, Zheng H, Cao Z, Chen E, Qian J.   +10 more
europepmc   +1 more source

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim, Minji Kim, Nani Jung, Sung Eun Kim, Ji Yoon Kim, Mi Ae Chu, Jung Eun Kwon, Yeo Hyang Kim, So Mi Lee, Ki‐Su Park, Jeong Eun Lee, Ye Jee Shim   +11 more
wiley   +1 more source

IL-10 family cytokines: source, receptors, and target cells.

, 2016
IL-10 family cytokines are produced by both immune and non-immune cells and signal through heterodimeric receptors expressed on diverse target cells. However, IL-26 might also mediate heterodimeric IL-20R1/IL-10R2 receptor-independent signaling.
Helmut Fickenscher (256277), Emmanuel Stephen-Victor (3215991), Jagadeesh Bayry (160872)   +2 more
core   +1 more source

IL-10 Receptor Blockade Delivered Simultaneously with Bacillus Calmette-Guérin Vaccination Sustains Long-Term Protection against Mycobacterium tuberculosis Infection in Mice. [PDF]

J Immunol, 2022
Dwivedi V, Gautam S, Headley CA, Piergallini T, Torrelles JB, Turner J.   +5 more
europepmc   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source