Results 231 to 240 of about 7,897,153 (261)
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Journal of Cellular Physiology, 2020
Esophageal cancer (EC) is the world's eighth most common malignant neoplasm and is ranked as the sixth leading cause of death related to cancer. Aberrant microRNA (miRNA) expression has been reported to be associated with esophageal squamous cell ...
Jianwei Tang +9 more
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Esophageal cancer (EC) is the world's eighth most common malignant neoplasm and is ranked as the sixth leading cause of death related to cancer. Aberrant microRNA (miRNA) expression has been reported to be associated with esophageal squamous cell ...
Jianwei Tang +9 more
semanticscholar +1 more source
Journal of Immunology, 2019
Key Points IL-11+CD4+ cells accumulate in the CSF and active brain RRMS lesions. IL-11 increased the numbers of CNS-infiltrating IL-17+CD4+ cells in RREAE. Passive transfer of IL-11–induced encephalitogenic CD4+ T cells induced severe RREAE.
Xin Zhang +9 more
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Key Points IL-11+CD4+ cells accumulate in the CSF and active brain RRMS lesions. IL-11 increased the numbers of CNS-infiltrating IL-17+CD4+ cells in RREAE. Passive transfer of IL-11–induced encephalitogenic CD4+ T cells induced severe RREAE.
Xin Zhang +9 more
semanticscholar +1 more source
Fish and Shellfish Immunology, 2019
Interleukins (ILs) are a subgroup of cytokines, which are molecules involved in the intercellular regulation of the immune system. These cytokines have been extensively studied in mammalian models, but systematic analyses of fish are limited.
Ying Wu +8 more
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Interleukins (ILs) are a subgroup of cytokines, which are molecules involved in the intercellular regulation of the immune system. These cytokines have been extensively studied in mammalian models, but systematic analyses of fish are limited.
Ying Wu +8 more
semanticscholar +1 more source
Science, 2019
Pulmonary Fibrosis In idiopathic pulmonary fibrosis (IPF), chronic activation of invasive fibroblasts causes fibrotic scar formation in the lungs. Patients with IPF present with progressive breathing difficulty, pulmonary hypertension, and respiratory failure. The pathophysiological mechanisms remain unclear.
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Pulmonary Fibrosis In idiopathic pulmonary fibrosis (IPF), chronic activation of invasive fibroblasts causes fibrotic scar formation in the lungs. Patients with IPF present with progressive breathing difficulty, pulmonary hypertension, and respiratory failure. The pathophysiological mechanisms remain unclear.
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Interleukin (IL)‐11‐mediated Signal Transductiona
Annals of the New York Academy of Sciences, 1995IL-11 is a multifunctional cytokine biologically related to IL-6, leukemia inhibitory factor (LIF), oncostatin M (OSM) and ciliary neurotrophic factor (CNTF). It has been shown that these cytokines can utilize common signal transducer, gp130. We have demonstrated that Jak tyrosine kinases, MAP kinases and pp90rsk are highly activated by IL-11 and ...
Y C, Yang, T, Yin
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1995
Abstract The nucleotide sequences of IL-11 cDNAs cloned from mouse and man (mouse sequence submitted to GenBank, human sequence GenBank accession number M37006) encode proteins with 199 amino acids (Fig. 1) (Paul eta/. 1990). At the amino acid level, the mouse and human proteins are highly conserved (88 per cent identity).
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Abstract The nucleotide sequences of IL-11 cDNAs cloned from mouse and man (mouse sequence submitted to GenBank, human sequence GenBank accession number M37006) encode proteins with 199 amino acids (Fig. 1) (Paul eta/. 1990). At the amino acid level, the mouse and human proteins are highly conserved (88 per cent identity).
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IL-11 is a potent anti-melanoma factor
2001Interleukin 11 (IL-11) is a pleiotropic cytokine initially identified as a factor stimulating proliferation of IL-6-dependet murine plasmacytoma cell line T11651. Today IL-11 is known to interact with variety of haematopoietic and nonhematopoietic cell types (for review see ref. 2).
H, Dams-Kozlowska +2 more
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IL-11, a pleiotropic cytokine: exciting new effects of IL-11 on gastrointestinal mucosal biology.
Stem cells (Dayton, Ohio), 1995Recombinant human interleukin 11 (rhIL-11) is a pleiotropic cytokine that stimulates bone marrow stem cells to proliferate and decreases intestinal mucosal injury produced by cytoablative drugs and radiation in animals. The effects of rhIL-11 were studied in a hamster model of oral mucositis and in two rat models of inflammatory bowel disease (IBD ...
J C, Keith +4 more
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