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Ethanol and Murine Interleukin (IL)‐12 Production
Alcoholism: Clinical and Experimental Research, 2000Background: Interleukin (IL)‐12 is a cytokine with protean effects against bacterial and intracellular pathogens. Induction of IL‐12 at the time of infection has salient effects on elimination of various microbes. This work describes the effect of exposure to ethanol on lipopolysaccharide (LPS)‐induced production of IL‐12 in mice and whether ethanol ...
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IL-12-Based therapy of malignancies
Drugs of Today, 2001Interleukin-12 (IL-12) is an important molecule that triggers the activation of natural killer (NK) cells and T-cells, the development of T helper type 1 (Th1) cells and the expression of antiangiogenic genes. Novel methods for IL-12 delivery include cell-based ex vivo gene therapy, viral vector-based gene therapy and DNA plasmid-based nonviral gene ...
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Current Cancer Drug Targets, 2017
Interleukin 12 (IL-12) is a pleiotropic cytokine that plays an essential role in Th1-type immune response against cancer, a condition where cells in a particular part of the body grow and reproduce uncontrollably.In this review, we describe the structural features of IL-12 family and their roles involved in cancer.IL-12 has been demonstrated to ...
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Interleukin 12 (IL-12) is a pleiotropic cytokine that plays an essential role in Th1-type immune response against cancer, a condition where cells in a particular part of the body grow and reproduce uncontrollably.In this review, we describe the structural features of IL-12 family and their roles involved in cancer.IL-12 has been demonstrated to ...
openaire +2 more sources