Results 141 to 150 of about 1,415,935 (292)

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

The balance between intrahepatic IL-17+ T cells and Foxp3+ regulatory T cells plays an important role in HBV-related end-stage liver disease [PDF]

, 2011
Yinghua Niu, Hongli Liu, Donglin Yin, Ruitian Yi, Tianyan Chen, Hong-an Xue, Shulin Zhang, Shumei Lin, Yingren Zhao   +8 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

IL-17; IL-17 receptor C (IL-17RC) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Th17 cell-derived IL-17 is dispensable for B cell antibody production

, 2012
Akiko Shibui, Eri Shimura, Aya Nambu, Sachiko Yamaguchi, Warren J. Leonard, Ko Okumura, Sumio Sugano, Katsuko Sudo, Susumu Nakae   +8 more
openalex   +2 more sources

Expression imbalance of IL-17/IL-35 in peripheral blood and placental tissue of pregnant women in preeclampsia

, 2020
Dan Lü, Qi Peng, Dandan Chen, Xiaojuan Chen, Min Jiang   +4 more
openalex   +1 more source

Imbalanced pro- and anti-Th17 responses (IL-17/granulocyte colony-stimulating factor) predict fatal outcome in 2009 pandemic influenza [PDF]

, 2011
Raquel Almansa, Lorenzo Socías, Paula Ramírez, Ignacio Martín‐Loeches, Jordi Vallés, Ana Loza, Jordi Rello, David J. Kelvin, Cristóbal León, Jesús Blanco, David Andaluz, Dariela Micheloud, Enrique Maraví, Raúl Ortíz de Lejarazu, Jesús F. Bermejo-Martín   +14 more
openalex   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Stress systems exacerbate the inflammatory response after corneal abrasion in sleep-deprived mice via the IL-17 signaling pathway [PDF]

Yunxia Xue, Pengyang Xu, Yu Hu, Sijing Liu, Ruyu Yan, Shutong Liu, Yan Li, Jun Liu, Ting Fu, Zhijie Li   +9 more
openalex   +1 more source