Results 161 to 170 of about 1,561,364 (334)

IL-17 and IL-22 Promote Keratinocyte Stemness in the Germinative Compartment in Psoriasis

, 2019
Anna‐Karin Ekman, Cecilia Bivik Eding, Ingemar Rundquist, Charlotta Enerbäck   +3 more
openalex   +2 more sources

301P Epigenetic modifications of IL-17 gene in patients with early breast cancer and healthy controls [PDF]

, 2023
Ljubica Radmilović Varga, Tihana Marić, Ana Katušić Bojanac, K. Horvatović, Marina Popović, Ana Kulić, Tajana Silovski, Maja Sirotković-Skerlev, Marija Križić, Krešimir Bulić, Hrvoje Silovski, Natalija Dedić Plavetić   +11 more
openalex   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

IL-17 induces reactive astrocytes and up-regulation of vascular endothelial growth factor (VEGF) through JAK/STAT signaling [PDF]

, 2017
Tao You, Yihui Bi, Jun Li, Mingkai Zhang, Xuezhou Chen, Keke Zhang, Jun Li   +6 more
openalex   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

IL-17 [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

666 Histopathologic Findings in Colonic Biopsies from a Cohort of Patients Treated with IL-17 Inhibitors. [PDF]

Ameya Patil, Rish K. Pai, Dora Lam‐Himlin, Jason Lewis, Kelsey McHugh, Marcela Salomao, Maxwell Smith, Tsung‐Teh Wu, Erinn Downs, Chirag Patel   +9 more
openalex   +1 more source

Parasitemia Induces High Plasma Levels of Interleukin-17 (IL-17) and Low Levels of Interleukin-10 (IL-10) and Transforming Growth Factor-ß (TGF-ß) in Pregnant Mice Infected with Malaria [PDF]

, 2015
Background: During pregnancy, the balanced dominance of the T helper17 response shifts to a Th2 response that is characterised by the production of IL-10, following the completion of the implantation process.
Fitri, Loeki Enggar, Rahmah, Zainabur, Sardjono, Teguh Wahju, Sasmito, Sujarot Dwi, Siswanto, Budi   +4 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source