Results 151 to 160 of about 6,990,253 (295)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Current perspectives on the role of IL-17 in autoimmune disease
, 2010 Hisakata YamadaDivision of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, JapanAbstract: Until recently, autoimmune diseases had been categorized as either Th1- or Th2-mediated diseases.
Hisakata Yamada
core
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
IL-17 induces macrophages to M2-like phenotype via NF-κB
, 2018 Jing Shen,1,* Xin Sun,2,* Bo Pan,1 Shoubo Cao,1 Jingyan Cao,1 Dehai Che,1 Fang Liu,1 Shuai Zhang,1 Yan Yu1 1Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, People’s Republic of China; 2Department of Cardiology ...
Shen J +8 more
core
IL-17 and synaptopodin protein expression of an anti-thy1 glomerulonephritic animal on d5.
, 2016 Representative images showing glomerular IL-17 and synaptopodin protein expression in renal tissue sections of an anti-thy1 glomerulonephritic animal on d5 after disease induction, in paraffin-embedded immunostained sections at x400 magnification.
Stephanie Krämer (3165525) +4 more
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Modulatory role of IL-17 in airway inflammation
, 2010 IL-17 orchestrates the accumulation of neutrophils to sites of infection and the release of microbicidal substances, and therefore plays a critical role in the innate immune response to infection.
Silverpil, Elin
core
Psoriasis: Targets and TherapyStefana Bucur,1,2 Elena-Daniela Serban,1 Bogdan Vasile Ileanu,3 Raluca Simona Costache,4,5 Alin Codrut Nicolescu,6 Traian Constantin,7,8 Daniel Octavian Costache,1,9 Maria-Magdalena Constantin1,2 1 2nd Department of Dermatology, “Carol Davila” University
Bucur S +7 more
doaj
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source