Results 181 to 190 of about 5,540,448 (336)

Inhibition of SIK1 Alleviates the Pathologies of Psoriasis by Disrupting IL-17 Signaling. [PDF]

Mediators Inflamm
Huang D, Sun H, Su L, Yang F, Huang D, Gao H, Cao M.   +6 more
europepmc   +1 more source

Role of IL-17A, IL-17F, and the IL-17 Receptor in Regulating Growth-Related Oncogene-α and Granulocyte Colony-Stimulating Factor in Bronchial Epithelium: Implications for Airway Inflammation in Cystic Fibrosis [PDF]

, 2005
Florencia McAllister, Adam C. Henry, James L. Kreindler, Patricia J. Dubin, Lauren Ulrich, Chad Steele, Jonathan D. Finder, Joseph M. Pilewski, Beatriz M. Carreno, Samuel J. Goldman, Jaana Pirhonen, Jay K. Kolls   +11 more
openalex   +1 more source

Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption

Molecular Oncology, Volume 19, Issue 4, Page 1203-1228, April 2025.
MiR‐99a‐5p/miR‐100‐5p (functionally identical) and miR‐125b‐5p microRNAs are downregulated in malignant germ cell tumors (GCTs). Combination replenishment of these microRNAs using mimics resulted in growth inhibition in representative cell lines, with consequent downregulation of target genes involved in cell cycle (confirmed by flow cytometry) and ...
Marta Ferraresso, Shivani Bailey, Luz Alonso‐Crisostomo, Dawn Ward, Christos Panayi, Zachary G. L. Scurlock, Harpreet K. Saini, Stephen P. Smith, James C. Nicholson, Anton J. Enright, Cinzia G. Scarpini, Nicholas Coleman, Matthew J. Murray   +12 more
wiley   +1 more source

The role of IL-17 family cytokines in cardiac fibrosis. [PDF]

Front Cardiovasc Med
Huang L.
europepmc   +1 more source

Gut microbiota diversity is prognostic and associated with benefit from chemo‐immunotherapy in metastatic triple‐negative breast cancer

Molecular Oncology, Volume 19, Issue 4, Page 1229-1243, April 2025.
We assessed the associations between the gut microbiota and outcome in metastatic triple‐negative breast cancer patients treated with chemotherapy alone or chemotherapy in combination with immunotherapy. Our data indicate that high gut microbiota alpha diversity was associated with improved clinical outcome and with benefit from immunotherapy.
Andreas Ullern, Kristian Holm, Andreas Hagen Røssevold, Nikolai Kragøe Andresen, Corinna Bang, Ole Christian Lingjærde, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +8 more
wiley   +1 more source

HDAC3 inhibitors induce drug resistance by promoting IL-17 A production by T cells. [PDF]

Sci Rep
Chen H, Qin A, Xu F, Guo S, Zhang G, Zhang A, Li W, Tian F, Zheng Q.   +8 more
europepmc   +1 more source

Vertical inhibition of p110α/AKT and N‐cadherin enhances treatment efficacy in PIK3CA‐aberrated ovarian cancer cells

Molecular Oncology, Volume 19, Issue 4, Page 1132-1154, April 2025.
PIK3CA amplification and PIK3CA mutation enhance ovarian tumorigenicity through an activation of AKT, which phosphorylates YAP at Ser127. This Ser127 phosphorylation leads to the retention of YAP in the cytoplasm and triggers RAC1 activity, promoting cell migration. Additionally, AKT activation increases expression of N‐cadherin, which further enhances
Shibo Zhang, Hei Ip Hong, Victor C. Y. Mak, Yuan Zhou, Yiling Lu, Guanglei Zhuang, Lydia W. T. Cheung   +6 more
wiley   +1 more source

The crucial role of neutrophil extracellular traps and IL-17 signaling in indomethacin-induced gastric injury in mice. [PDF]

Sci Rep
Hou Y, Wang W, Ye J, Sun L, Zhou S, Zheng Q, Shi Y, Chen Y, Yao J, Wang L, Yan X, Wan R, Chen S, Li Y.   +13 more
europepmc   +1 more source

A mechanism of IL-17 action in the rheumatoid arthritis

, 2001
Shigeru Kotake, Naoyuki Kamatani
openalex   +2 more sources

CD8+ IL-17-Producing T Cells Are Important in Effector Functions for the Elicitation of Contact Hypersensitivity Responses [PDF]

, 2006
Donggou He, Lizhi Wu, Hee Kyung Kim, Hui Li, Craig A. Elmets, Hui Xu   +5 more
openalex   +1 more source