Results 241 to 250 of about 5,540,448 (336)

Study on serum TL1A levels and their correlation with Th17 cells, IL-17 and IL-21 in children with Graves' disease. [PDF]

Front Immunol
Hao L, Yang J, Lian B, Yin C, Xiao Y, Liu Y.   +5 more
europepmc   +1 more source

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

Molecular Oncology, Volume 19, Issue 5, Page 1404-1421, May 2025.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock, Lina Benzien, Sandra Lange, Maja Huehns, Alexandra Runge, Catrin Roolf, Anett Sekora, Gudrun Knuebel, Hugo Murua Escobar, Christian Junghanss, Anna Richter   +10 more
wiley   +1 more source

Pasteurella multocida Serotype D Infection Induces Activation of the IL-17 Signaling Pathway in Goat Lymphocytes. [PDF]

Microorganisms
Fu Y, Meng Y, Qian H, Chen T, Chen X, Chen Q, Gao H, Man C, Du L, Chen S, Wang F.   +10 more
europepmc   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, Volume 19, Issue 5, Page 1347-1370, May 2025.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

Comparative Analysis of Serum BAFF and IL-17 Levels Pre- and Post-Antipsychotic Treatment for Acute Schizophrenia. [PDF]

Int J Mol Sci
Samoud S, Mtiraoui A, Zamali I, Galai Y, Hannachi N, Manoubi W, Nakhli J, Louzir H, Kissi YE.   +8 more
europepmc   +1 more source

TLR4 Mediates Vaccine-Induced Protective Cellular Immunity to Bordetella pertussis: Role of IL-17-Producing T Cells

, 2006
Sarah Higgins, Andrew Jarnicki, Ed C. Lavelle, Kingston H. G. Mills   +3 more
openalex   +1 more source

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

Molecular Oncology, Volume 19, Issue 5, Page 1299-1309, May 2025.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen, Saurav Subedi, Federico La Manna, Sofia Jarrin, Irida Papapostolou, Marianna Kruithof‐de Julio, Christine Peinelt   +6 more
wiley   +1 more source

IL-17 signaling pathway in SPP1⁺ macrophages drives digestive tract cancer progression. [PDF]

Genes Dis
Wei Y, Xu Y, Zeng Y, Zhang A, Xing X, Liu W.   +5 more
europepmc   +1 more source

Two-Sided Roles of IL-27: Induction of Th1 Differentiation on Naive CD4+ T Cells versus Suppression of Proinflammatory Cytokine Production Including IL-23-Induced IL-17 on Activated CD4+ T Cells Partially Through STAT3-Dependent Mechanism

, 2006
Takeru Yoshimura, Atsunobu Takeda, Shinjiro Hamano, Yoshiyuki Miyazaki, Ichiko Kinjyo, Tatsuro Ishibashi, Akihiko Yoshimura, Hiroki Yoshida   +7 more
openalex   +1 more source

Innate source of IL-17 [PDF]

Nature Reviews Immunology, 2009
openaire   +1 more source