Results 251 to 260 of about 1,564,564 (287)

Diagnostic utility of IL-18 plasma levels in distinguishing abdominal from non-abdominal sepsis. [PDF]

Front Immunol
Herminghaus A, Totskyi M, Vollmer C, Dimski T, Brandenburger T, Kuebart A, Rinderknecht H, Bergmann CB, Vernikouskaya I, Bülow JM, Becker N, Relja B.   +11 more
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Correlation between NLRP6 inflammasome and the levels of inflammatory cytokines IL-1b and IL-18 in serum of patients with Meniere's disease. [PDF]

J Med Biochem
Li M, Zhou Y, Liu Z, Jin X.
europepmc   +1 more source

IL-18 and IL-18BP: A Unique Dyad in Health and Disease. [PDF]

Int J Mol Sci
Novick D.
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KL-6, IL-18, and S100A8/A9 are biomarkers of connective tissue disease-associated interstitial lung disease. [PDF]

Medicine (Baltimore)
Liu Y, Xu S, Shi C, Yang Q.
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Mast cells boost anti-tumor potency of MAIT cells via inflammasome-dependent secretion of IL-18. [PDF]

Nat Commun
Fan F, Wang J, Liu K, Zhang S, Gao J, Li X, Ma J, Zhao Y, Li T, Su H, Yang X, Han H, Huang Q, Zhang Y, Pan Y, Ye T, Hu H, Sun Y, Li F, Cao Z, Zhang Y, Zhang X, Chen H.   +22 more
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IL-18 gene polymorphisms affect IL-18 production capability by monocytes.

IL-18 gene polymorphisms affect IL-18 production capability by monocytes.
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IL-18 gene polymorphisms affect IL-18 production capability by monocytes

Biochemical and Biophysical Research Communications, 2006
We previously demonstrated a significant association between IL-18 gene polymorphism 105A/C and asthma. In this study, we investigated the relationship of IL-18 gene polymorphism to IL-18 production capability by monocytes. The frequency of gene polymorphisms including IL-18-105A/C and IL-18--137G/C was determined by PCR analyses.
Junsuke, Arimitsu, Toru, Hirano, Shinji, Higa, Mari, Kawai, Tetsuji, Naka, Atsushi, Ogata, Yoshihito, Shima, Minoru, Fujimoto, Tomoki, Yamadori, Keisuke, Hagiwara, Tomoharu, Ohgawara, Yusuke, Kuwabara, Ichiro, Kawase, Toshio, Tanaka   +13 more
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Immunotherapeutic Applications of IL-18

Immunotherapy, 2012
To become active and extracellularly released, IL-18 needs post-translational processing by the cytoplasmic enzyme caspase-1, which has high sequence homology with apoptotic cell death-associated enzymes in Caenorhabditis elegans. Furthermore, the receptor for IL-18 shares the signal transduction pathway with the Toll-like receptor, which highly ...
Hiroko, Tsutsui, Kenji, Nakanishi
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IL-18 and skin inflammation

Autoimmunity Reviews, 2009
IL-18 belongs to the IL-1 family of cytokines and has recently regained interest in the context of inflammasome activation. The inflammasome dependent caspase 1 cleaves pro-IL-18 into the active form - similar to what is known for IL-1ss. Still, the action and importance of IL-18 are not completely understood.
Miriam, Wittmann, Andrew, Macdonald, Julius, Renne   +2 more
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Human Anti–Human IL-18 Antibody Recognizing the IL-18–Binding Site 3 with IL-18 Signaling Blocking Activity

The Journal of Biochemistry, 2005
IL-18 is an important regulator in both innate and acquired immune responses. The aberrant expression of IL-18 is associated with severe inflammatory conditions, such as autoimmune diseases and allergies. Thus, human antibodies with inhibitory activity on IL-18 signaling may be useful for therapeutic applications. We report here the first establishment
Takayuki, Hamasaki, Shuhei, Hashiguchi, Yuji, Ito, Zenichiro, Kato, Kenji, Nakanishi, Toshihiro, Nakashima, Kazuhisa, Sugimura   +6 more
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