Results 51 to 60 of about 7,505,048 (245)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási +14 more
wiley +1 more source
Monaldi Archives for Chest DiseaseTuberculosis (TB) regained its position globally as the leading cause of mortality from a single infectious agent after being surpassed by COVID-19 for 3 years consecutively.
Karan Gupta +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta +6 more
wiley +1 more source
The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
A role for IL-18 in protective immunity against Mycobacterium tuberculosis.
, 2009 Tuberculosis remains the most hazardous bacterial infection worldwide. The causative agent, Mycobacterium tuberculosis, is a facultative intracellular pathogen of resting MPhi.
Hagens, Kristine +20 more
core +1 more source
Mediators of Inflammation, 2014 Proinflammatory cytokine IL-18 has been shown to be elevated in the sera of ovarian carcinoma patients. The aim of the study was to examine the levels and cellular origin of IL-18, IL-18 binding protein, and IL-18 receptor in normal and cancerous ovarian
Liat Medina +5 more
doaj +1 more source
Zdorovʹe Rebenka, 2014 The review presents the characteristics of IL-1F4 (IL-18), its mechanisms of action and value in the development of inflammatory response.
A.Ye. Abaturov +2 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters +17 more
wiley +1 more source
IL-18 decreases TEER in Caco2 monolayers.
, 2018 The TEER was measured during 24 hours after addition of 10 ng/ml of IL-18, 10 ng/ml IL-1β or 100 ng/ml Tat to the cell monolayers. Note dramatic decrease of the TEER occurring at hour 6 post-exposure by both IL-18 and Tat.
Vikram Mehraj (376026) +7 more
core +1 more source
INFLAMMASOME NLRP1 DISTINCTIVE FEATURES IN ATOPIC CONDITIONS
Медицина в Кузбассе, 2023 The review article focuses on the NLRP1 inflammasome, which was discovered before the others but has been the least investigated. The emergence of the inflammasome in innate immunity container cells is an early event that precedes the development of any ...
Денис Сергеевич Загрешенко +5 more
doaj