Results 91 to 100 of about 6,541,017 (281)

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte, Hannah Koch, Olivia A. Coughlin, Jillian R. Bouck, Allie Carter, Seethal A. Jacob   +5 more
wiley   +1 more source

Image_5_ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases.JPEG [PDF]

, 2018
In gut epithelium, IL-22 transmits signals through STAT3 phosphorylation (pSTAT3) which provides intestinal immunity. Many components in the IL-22-pSTAT3 pathway have been identified as risk factors for inflammatory bowel disease (IBD) and some of them ...
Ming-Che Liu (134182), Ching-Feng Cheng (324818), Janaki N. Sudhakar (5927741), Doaa Glal (5927738), Yen-Chun Liu (50962), Hung-Yu Chiang (5927744), Jr-Wen Shui (5927747), Hsueh-Han Lu (1802653)   +7 more
core   +1 more source

Psychosocial Functioning After Pediatric Bone Sarcoma: Generic and Survivor‐Specific Outcomes in Adolescent and Young Adult Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek, Heleen Maurice‐Stam, Laura R. Beek, Jennifer van Dijk, Marjolein E. M. Langemeijer, Relinde W. Slooff‐Lentink, Alied M. van der Aa‐van Delden, Anne Westerweel, Marloes van Gorp, Hendrik W. B. Schreuder, Lianne M. Haveman, W. Peter Bekkering, Leonie G. Tigelaar, Johannes H. M. Merks, Martha A. Grootenhuis   +14 more
wiley   +1 more source

Induction of IL-22 protein and IL-22-producing cells in rainbow trout Oncorhynchus mykiss

Developmental & Comparative Immunology, 2019
IL-22 is a critical cytokine which is involved in modulating tissue responses during inflammation, and is produced mainly by T cells and innate leucocytes. In mammals, IL-22 is a key component in mucosal defences, tissue repair, epithelial cell survival and proliferation.
Hu, Yehfang, Carpio, Yamila, Scott, Callum, Alnabulsi, Ayham, Alnabulsi, Abdo, Wang, Tingyu, Liu, Fuguo, Monte, Milena, Wang, Tiehui, Secombes, Christopher J.   +9 more
openaire   +3 more sources

Potential involvement of IL-22 and IL-22-producing cells in the inflamed salivary glands of patients with Sjögren's syndrome [PDF]

Annals of the Rheumatic Diseases, 2012
In chronic inflammatory disorders, interleukin (IL)-22 may act either as a protective or as a pro-inflammatory cytokine. At mucosal sites, IL-22 is mainly produced by CD4(+) T cells and by a subset of mucosal natural killer (NK) cells expressing the receptor NKp44 (NKp44(+) NK cells). The aim of this study was to investigate the IL-22 expression in the
CICCIA, Francesco, GUGGINO, Giuliana, Rizzo A, FERRANTE, Angelo, RAIMONDO, Stefania, GIARDINA, Annarita, DIELI, Francesco, CAMPISI, Giuseppina, ALESSANDRO, Riccardo, TRIOLO, Giovanni   +9 more
openaire   +4 more sources

Il modello di business [PDF]

, 2011
Il capitolo presenta i risultati di un questionario rivolto agli intermediari bancari italiani che operano nel comparto del microcredito finalizzato ad indagare lo stato dell'arte di questo business (margini prodotti, modalità di valutazione del rischio,
PORRETTA, Pasqualina
core  

IL-22 produced by type 3 innate lymphoid cells (ILC3s) reduces the mortality of type 2 diabetes mellitus (T2DM) mice infected with Mycobacterium tuberculosis [PDF]

, 2019
Previously, we found that pathological immune responses enhance the mortality rate of Mycobacterium tuberculosis (Mtb)-infected mice with type 2 diabetes mellitus (T2DM).
Rajesh Kumar Radhakrishnan (5587778), Buka Samten (3404951), Ramya Sivangala Thandi (8098553), Venkata Sanjeev Kumar Neela (5587784), Ramakrishna Vankayalapati (306095), Madeline Kay McAllister (8098556), Deepak Tripathi (690264), Padmaja Paidipally (690262), Kamakshi Prudhula Devalraju (6009380), Vijaya Lakshmi Valluri (7422743)   +9 more
core   +1 more source

IL-21 Induces an Imbalance of Th17/Treg Cells in Moderate-to-Severe Plaque Psoriasis Patients

Frontiers in Immunology, 2019
Background: Psoriasis is a chronic immune-mediated inflammatory skin disease, with over-activated interleukin (IL)-17-producing CD4+ T cells (Th17) and repressed regulatory T (Treg) cells.
Yuling Shi, Yuling Shi, Zeyu Chen, Zeyu Chen, Zihan Zhao, Zihan Zhao, Yingyuan Yu, Yingyuan Yu, Huayu Fan, Huayu Fan, Xiaoguang Xu, Xiaolin Bu, Jun Gu   +12 more
doaj   +1 more source

CircRAB3B suppresses proliferation, motility, cell cycle progression and promotes the apoptosis of IL-22-induced keratinocytes depending on the regulation of miR-1228-3p/PTEN axis in psoriasis

Autoimmunity, 2021
Introduction Psoriasis is an immune-related chronic skin disease, and interleukin-22 (IL-22) is involved in psoriasis pathogenesis through promoting proliferation and migration abilities of keratinocytes.
Jiajing Lu, Xin Xu, Ying Li, Ning Yu, Yangfeng Ding, Yuling Shi   +5 more
doaj   +1 more source

Ironic Medications: A Narrative‐Based Psycho‐Educational Intervention to Explore Patient–Provider Communication in Adolescents With Haematological Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa, Elena Pagani Bagliacca, Selena Russo, Giulia Rampoldi, Maria Grazia Strepparava, Adriana Cristina Balduzzi, Andrea Biondi, Marco Spinelli   +7 more
wiley   +1 more source