Results 181 to 190 of about 6,541,017 (281)

Il settore Lattanzi della necropoli di Norchia ed il contesto della tomba 3 [PDF]

Il capitolo presenta il contesto e lo scavo della tomba della necropoli dei Lattanzi a Norchia, in cui nel 2024 è stato rinvenuto uno stamnos decorato e ...
Daniel Morleghem
core  

Non-canonical IL‑22 receptor signaling remodels the oral mucosal barrier during Candida albicans immunosurveillance. [PDF]

Nat Commun
Millet N, Sekar J, Solis NV, Miao J, Millet A, Aggor FEY, Wildeman A, Cook ME, Davari A, Peters BM, Lionakis MS, Gaffen SL, Jendzjowsky N, Filler SG, Swidergall M.   +14 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Evaluation of Serum Levels of IL-17 and IL-22 in Leprosy: A Case-Control Study. [PDF]

Cureus
Nanda A, Mahendra A, Dabhra A, Gupta S.
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

IL-22 attenuates MAFLD progression by modulating oxidative stress and ferroptosis. [PDF]

Sci Rep
Li S, Zhang Y, Li P, Xue X, Huo L.
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Injectable pH-responsive carboxymethyl cellulose hydrogel for sustained delivery of IL-22 in the treatment of alcoholic liver disease. [PDF]

J Nanobiotechnology
Zhou H, Yang D, Gu R, Song Y, Wei Z, Qian C, Yang N, Liu J, Ye S, Xu T.   +9 more
europepmc   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Comprehensive Transcriptomic Profiling of Nonatopic Prurigo Nodularis in Korean Patients Reveals Il-22-driven Epidermal Stress and Neuro-immuno-fibrotic Remodelling. [PDF]

Acta Derm Venereol
Kim HS, Kim YS, Yosipovitch G.
europepmc   +1 more source