Results 251 to 260 of about 63,742,190 (280)

Metabolic regulation of T cell production of IL-10 and IL-22 protects against intestinal inflammation. [PDF]

Precis Clin Med
Liu H, Zhao X, Yu T, Yu Y, Yao S, Yang W, Cong Y.   +6 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Dysregulation of Treg/Th17 Balance and Intracellular Expression of IL-21 and IL-22 in the Pathogenesis of Gestational Hypertension. [PDF]

J Clin Med
Kwiatek M, Kwaśniewski W, Gęca T, Grywalska E, Rahnama-Hezavah M, Mertowski S, Urbanowicz T, Kowalkowska ME, Krasiński M, Kwaśniewska A, Brązert M.   +10 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Therapeutic potential of recombinant IL-22BP in psoriasis: suppression of IL-22/STAT3 signaling in mice. [PDF]

AMB Express
Chen X, Zeng T, Fang F, Tian Q, Li Y, Zhou W, Gong B, Tian N, Zhang J, Xiao Y.   +9 more
europepmc   +1 more source

IL-22 inhibits ferroptosis and attenuates ischemia-reperfusion-induced acute kidney injury: Association with activation of the P62-Keap1-Nrf2 signaling pathway. [PDF]

PLoS One
Zhang L, Luo F, Chai Y, Sun L, Wang X, Yin L, Luo C.   +6 more
europepmc   +1 more source

An Update on IL-22 Therapies in Alcohol-Associated Liver Disease and Beyond. [PDF]

Am J Pathol
Fu L, Yokus B, Gao B, Pacher P.
europepmc   +1 more source

Relationship of the Specific Inflammatory Cytokines KLK5, IL-8, and IL-22 with <i>Demodex</i> Density and Risk Factors in Rosacea. [PDF]

J Inflamm Res
Xu J, Zhang Y, Ci C, Lu X, Hu X, Zhao J, Li Y.   +6 more
europepmc   +1 more source

A20's linear ubiquitin-binding motif restrains pathogenic activation of Th17 cells and IL-22-driven enteritis. [PDF]

J Clin Invest
Bowman CJ, Stibor DM, Sun X, Lenci N, Shimizu H, Yamashita EF, Advincula R, Kim MC, Turnbaugh JA, Sun Y, Razani B, Turnbaugh PJ, Ye CJ, Malynn BA, Ma A.   +14 more
europepmc   +1 more source