Results 111 to 120 of about 63,292,925 (286)

Assessment of The Impact of Apremilast on Levels of IL-17, IL-23, and Lipids in Obese Psoriatic Patient

مجلة كلية الطب
Background: Psoriasis is an immune-mediated inflammatory disease with unknown aetiology that may be associated with the defect in proliferation and differentiation of the keratinocytes related to inflammatory cell infiltration.
Haitham M. Saad, Adil A. Noaimi, Halla Gh. Mahmood   +2 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

IL-12-and IL-23 in health and disease

, 2014
Interleukin (IL)-12 and IL-23 play important roles in the development of experimental autoimmune disease models and numerous afflictions affecting humans.
Becher, Burkhard; https://orcid.org/, Kulig, Paulina, Croxford, Andrew L, Croxford AL, Becher B, Kulig P   +5 more
core   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Cytoplasmic tail of IL-13Ralpha2 regulates IL-4 signal transduction

, 2009
IL (interleukin)-4 and IL-13 are key cytokines in the pathogenesis of allergic inflammatory disease. IL-4 and IL-13 share many functional properties as a result of their utilization of a common receptor complex comprising IL-13Ralpha1 (IL-13 receptor ...
Donna E. Davies, Holgate, Stephen T, Isabelle Kirby, Ida Karin Nordgren, Tavassoli, Ali, Davies, Donna E, Holloway, John W, Andrews, Allison-Lynn, Stephen T. Holgate, Nordgren, Ida Karin, John W. Holloway, Kirby, Isabelle, Allison-Lynn Andrews, Ali Tavassoli   +13 more
core   +1 more source

Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNγ  production [PDF]

, 2009
IL-23/IL-17-induced neutrophil recruitment plays a pivotal role in rheumatoid arthritis (RA). However, the mechanism of the neutrophil recruitment is obscure.
Foo Y. Liew, Ferreira, Sergio H., Cunha, Fernando Q., Cunha, Thiago Mattar, Fernando Q. Cunha, Ferreira, Seérgio Henrique, Karla S. S. Fernandes, Silvio M. Vieira, Waldiceu A. Verri, McInnes, Iain B., Sergio H. Ferreira, Lemos, Henrique Paula, Liew, Foo Y., Thiago M. Cunha, Souto, Fabrício Oliveira, Renata Grespan, Manfredo Vieira, Silvio, Cunha, Thiago M., Souto, Fabricio O., Lemos, Henrique P., Fabricio O. Souto, Vieira, Silvio M., Fernandes, Karla S. S., Henrique P. Lemos, Verri, Waldiceu A., Grespan, Renata, Fernandes, Karla S., Cunha, Fernando Queiroz, Iain B. McInnes, VERRI JR., Waldiceu A.   +29 more
core   +1 more source

Profile of tildrakizumab-asmn in the treatment of moderate-to-severe plaque psoriasis: evidence to date

Psoriasis: Targets and Therapy, 2018
Kristen M Beck, Isabelle M Sanchez, Eric J Yang, Wilson Liao Department of Dermatology, University of California San Francisco, San Francisco, CA, USA Abstract: Plaque psoriasis is an immune-mediated skin disease that affects roughly 3% of adults in the ...
Beck KM, Sanchez IM, Yang EJ, Liao W
doaj  

IL-12 family cytokines and autoimmune diseases: A potential therapeutic target?

Journal of Translational Autoimmunity
In recent years, the discovery of IL-12 family cytokines, which includes IL-12, IL-23, IL-27, IL-35, and IL-39, whose biological functions directly or indirectly affect various autoimmune diseases.
Xiaoyu Cui, Wu Liu, Hanxue Jiang, Qihan Zhao, Yuehong Hu, Xinyue Tang, Xianli Liu, Haoran Dai, Hongliang Rui, Baoli Liu   +9 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

IL-23 및 p35을 발현하는 oncolytic adenovirus의 항종양 면역효과 및 세포성 면역반응 증대

, 2012
Graduate Program for Nanomedical Science/박사Cytokine immunogene therapy is a promising strategy for cancer treatment. Interleukin (IL)-12 boosts potent antitumor immunity by inducing T helper 1 (Th1) cell differentiation and stimulating cytotoxic T ...
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