Results 201 to 210 of about 1,375,213 (331)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Association of Serum IL-17A and IL-23 Levels With Alopecia Areata: A Cross-Sectional Comparative Study. [PDF]

Cureus
Talukder MS, Asaduzzaman ATM, Azad MAK, Uddin MJ, Dash PS, Ahmed WD.   +5 more
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Assessing T-Cell Profile Shifts through IL-23 Inhibition by Guselkumab on Psoriasis. [PDF]

JID Innov
Kanayama Y, Watanabe O, Sakurai M, Enomoto Y, Yamamoto A, Mashiko S, Sugiura Y, Miyashiro M, Masuda J, Morita A.   +9 more
europepmc   +1 more source

Table 1_Efficacy and safety of IL-17, IL-12/23, and IL-23 inhibitors for psoriatic arthritis: a network meta-analysis of randomized controlled trials.docx

Shan Gao (46743), Xingxing Xie (6293498), Ling Fan (2215240), Linyuan Yu (8929973)   +3 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

IL-23 tees off enthesitis [PDF]

Nature Reviews Immunology, 2012
openaire   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Adipose tissue IL-23 is associated with fasting blood glucose and HbA1c in overweight/obese individuals. [PDF]

Front Endocrinol (Lausanne)
Kochumon S, Bahman F, Albeloushi S, Al Madhoun A, Alzaid F, Tuomilehto J, Al-Mulla F, Ahmad R.   +7 more
europepmc   +1 more source

Aldo Ferrari. « Gli Armeni e la spedizione persiana di Pietro il Grande (1722-23) ». Annali di Ca’ Foscari, 35/3, (1996), pp. 187-198. [PDF]

, 2002
Rudi Matthee
openalex   +1 more source