Results 51 to 60 of about 8,411,708 (236)
IL-23 regulated signaling pathways in the OT-II/Th17 phosphoproteome.
, 2020 (a) Graph represents the statistical significance (-log(p-value)) of the top 10 molecular and cellular processes overrepresented among the IL-23-responsive phosphoproteins. Inset numbers indicate the number of proteins included in each group.
Candelas Álvarez-Salamero (8611707) +6 more
core +1 more source
Zhongguo shiyan zhenduanxue, 2011 目的探讨结直肠癌进展过程中,患者血清中几种细胞因子水平的变化及其在肿瘤进程中的意义。方法纳入50例患者及20例健康志愿者,运用ELISA方法检测各组血清IL-23I、L-17I、L-10和IFN-α水平的变化。结果结直肠癌患者血清IL-23和IL-10水平显著高于对照组,而且Ⅳ期患者血清IL-10水平显著高于Ⅰ、Ⅱ、Ⅲ期。结论与IL-17和IFN-α相比,患者血清中IL-23和IL-10表达水平显著增加;此外,患者血清中IL-10的高水平表达可能促进了结直肠癌的发展。
吕坤, 张莺莺
doaj
İstanbul Kuzey Klinikleri, 2019 OBJECTIVE: In this study, we aimed to assess the effects of long- and short-term IL-15 cytokine exposure of human monocyte-derived curdlan-matured dendritic cells (DCs) on the production of Th17 cell-polarizing cytokine IL-23 and subsequent Th17 cell ...
Ahmet Eken +10 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
IL-23 induces pRLC-S20 through ROCK dependent mechanisms in Th17 cells.
, 2020 (a) Total lymph node cells from Il23r-gfp reporter mice were processed for analysis of IL-23R (GFP) expression by flow cytometry. Representative contour plots show CD44 and IL-23R/GFP expression in the CD3+CD4+ population, and inset number represents the
Candelas Álvarez-Salamero (8611707) +6 more
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Interleukin-12 family cytokines and sarcoidosis
Frontiers in Pharmacology, 2014 Sarcoidosis is a systemic granulomatous disease predominantly affecting the lungs. It is believed to be caused by exposure to pathogenic antigens in genetically susceptible individuals but the causative antigen has not been identified.
Sabine eRingkowski +3 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
The Canadian Journal of UrologyPenile fracture is a rare clinical entity that occurs secondary to direct trauma to an erect penis, most commonly during sexual intercourse. Specifically, increased pressure within the corpus cavernosa results in rupture of the tunica albuginea ...
Conor B. Driscoll +3 more
doaj +1 more source