The role of IL-23 in the immunopathogenesis of psoriasis [PDF]
F1000 Biology Reports, 2010 In just 10 years from its discovery in 2000, interleukin-23 has quickly moved from being recognized as a pro-inflammatory cytokine to a key player and potential therapeutic target in psoriasis.
Meglio, Paola Di, Nestle, Frank O
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Antitumor and Antimetastatic Activity of IL-23 [PDF]
The Journal of Immunology, 2003 Abstract The structure and T cell stimulatory effects of the recently discovered cytokine IL-23 are similar to, but distinct from, those of IL-12. Although the antitumor activities of IL-12 are well characterized, the effect of IL-23 on tumor growth is not known. In this study, murine CT26 colon adenocarcinoma and B16F1 melanoma cells
Lo, C.-H. +10 more
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Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1 [PDF]
, 2010 If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine host responses targeting infection. Thus, we sought to characterize the immediate cytokine storm
Nicole Darsow +38 more
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The effect of periodontal therapy on IL-17 and IL-23 in Gingival Crevicular Fluid (GCF) of patients with severe periodontitis [PDF]
Caspian journal of dental research, 2013 Introduction: Cytokines are the important factors in the progression of periodontal diseases. The aim of this study was to find out the effect of the first phase of the periodontal therapy on the amount of existing IL-17 and IL-23 in gingival crevicular ...
Marzieh Rohaninasab +3 more
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Innate lymphoid cells exhibited IL-17-expressing phenotype in active tuberculosis disease
BMC Pulmonary Medicine, 2021 Background Innate lymphoid cells (ILCs), as an important group of innate immunity, could respond rapidly to Mycobacterium tuberculosis (Mtb) infection.
Linyue Pan +11 more
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Frontiers in Immunology, 2017 Paracoccidioidomycosis (PCM), a chronic granulomatous disease caused by the thermally dimorphic fungus Paracoccidioides brasiliensis and Paracoccidioides lutzii, has the highest mortality rate among systemic mycosis.
Fabrine Sales Massafera Tristão +6 more
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Immunogenicity to biological drugs in psoriasis and psoriatic arthritis
Clinics, 2021 Monoclonal antibodies or fusion proteins, defined as biological drugs, have modified the natural history of numerous immune-mediated disorders, allowing the development of therapies aimed at blocking the pathophysiological pathways of the disease ...
Fernando Valenzuela, Rodrigo Flores
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IL-23-induced IL-17 production by activated human T cells in a dose-dependent manner
, 2011 Copyright information:Taken from "IL-23 induces human osteoclastogenesis via IL-17 , and anti-IL-23 antibody attenuates collagen-induced arthritis in rats"http://arthritis-research.com/content/9/5/R96Arthritis Research & Therapy 2007;9(5):R96-R96 ...
Manabu Kawamoto (18939) +6 more
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IL-23-induced osteoclastogenesis from cultured human peripheral blood mononuclear cells
, 2011 Copyright information:Taken from "IL-23 induces human osteoclastogenesis via IL-17 , and anti-IL-23 antibody attenuates collagen-induced arthritis in rats"http://arthritis-research.com/content/9/5/R96Arthritis Research & Therapy 2007;9(5):R96-R96 ...
Manabu Kawamoto (18939) +6 more
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Differential regulation of interleukin-17 and interferon-y production in inflammatory bowel disease [PDF]
, 2010 PhDBackground and Aims. Interleukin (IL)-17 is now known to be involved in a number of chronic inflammatory disorders. However, the mechanisms regulating its production in inflammatory bowel disease (IBD) are still unclear. Methods.
Rovedatti, Laura
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