Results 61 to 70 of about 1,375,213 (331)
Regulatory effects of C5a on IL-17A, IL-17F, and IL-23
Frontiers in Immunology, 2013 The complement anaphylatoxin, C5a, through binding to its receptors (C5aR or C5L2), has important biological properties for recruitment and activation of phagocytes.
Jamison J. Grailer +2 more
doaj +1 more source
Efficacy of anti‐
, 2023 Luca Mastorino +9 more
openalex +1 more source
Myc Cooperates with Ras by Programming Inflammation and Immune Suppression. [PDF]
, 2017 The two oncogenes KRas and Myc cooperate to drive tumorigenesis, but the mechanism underlying this remains unclear. In a mouse lung model of KRasG12D-driven adenomas, we find that co-activation of Myc drives the immediate transition to highly ...
Brown Swigart, Lamorna +7 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard +8 more
wiley +1 more source
Tildrakizumab in the treatment of psoriasis: latest evidence and place in therapy. [PDF]
, 2019 Psoriasis is a chronic inflammatory disorder that is clinically characterized by scaly cutaneous plaques. New evidence suggests that dysregulation of interleukin (IL)-23, a key cytokine in the T-helper-17 pathway, plays a vital role in the development of
Lee, Erica B +4 more
core
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis +13 more
wiley +1 more source
Antitumor and Antimetastatic Activity of IL-23 [PDF]
The Journal of Immunology, 2003 Abstract The structure and T cell stimulatory effects of the recently discovered cytokine IL-23 are similar to, but distinct from, those of IL-12. Although the antitumor activities of IL-12 are well characterized, the effect of IL-23 on tumor growth is not known.
Lo, C.-H. +10 more
openaire +2 more sources
Treatment with Anti-Interleukin 23 Antibody Ameliorates Disease in Lupus-Prone Mice [PDF]
, 2013 Interleukin 23 receptor expressing IL-17 producing T cells have been shown to be important in the development of murine lupus. The usefulness of IL-23 inhibition in ameliorating lupus nephritis is unknown.
Kampagianni, Ourania +2 more
core +2 more sources
Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li +6 more
wiley +1 more source
Targeting IL-23: Insights into the pathogenesis and the treatment of psoriasis
Indian Journal of Dermatology, 2010 Therapeutic experience strongly supports the use of TNF antagonists as important modalities in the treatment of psoriatic arthritis and plaque psoriasis.
Lima Hermenio, Kimball Alexandra
doaj