Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity. [PDF]
Cortez VS +13 more
europepmc +1 more source
An innate IL-25-ILC2-MDSC axis creates a cancer-permissive microenvironment for <i>Apc</i> mutation-driven intestinal tumorigenesis. [PDF]
Jou E +12 more
europepmc +1 more source
Il ritratto di Alfonso il Magnanimo nell'inedito Novencarmen di Lorenzo Valla
La relazione illustra le modalità di rappresentazione e celebrazione di Alfonso il Magnanimo nell'inedito poema polimetrico di Lorenzo Valla intitolato ...
IACONO, ANTONIETTA
core
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
IL-25-ILC2-IL-13 axis improves traumatic brain injury by mediating CXCL-10-dependent regulation of blood brain barrier integrity. [PDF]
Peng M +6 more
europepmc +1 more source
IL-25-induced shifts in macrophage polarization promote development of beige fat and improve metabolic homeostasis in mice. [PDF]
Li L +12 more
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The IL-25-dependent tuft cell circuit driven by intestinal helminths requires macrophage migration inhibitory factor (MIF). [PDF]
Varyani F +11 more
europepmc +1 more source

