Results 181 to 190 of about 1,543,952 (322)

One mechanism of glucocorticoid action in asthma may involve the inhibition of IL-25 expression

, 2016
Wei Lü, Chao Lü, Chengming Zhang, Chenghao Zhang   +3 more
openalex   +2 more sources

Economia agraria e pianificazione economica territoriale nel Parco nazionale del Sagarmatha (Everest, Nepal) [PDF]

In questo quaderno vengono pubblicati i contributi scientifici che sono stati presentati alla conferenza nazionale avente per tema “Economia agraria e pianificazione economica territoriale nel Parco Nazionale del Sagarmatha (Everest, Nepal)”, che si è ...
Fabrizio Luciani, Silvia Micheli
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Defining the Roles of IL-33, Thymic Stromal Lymphopoietin, and IL-25 in Human Asthma

, 2014
Derek E. Byers
openalex   +2 more sources

Tuft cell‐derived IL‐25 activates and maintains ILC2 [PDF]

Immunology & Cell Biology, 2016
Konrad, Gronke, Andreas, Diefenbach
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

IL-25 and IL-33 Contribute to Development of Eosinophilic Airway Inflammation in Epicutaneously Antigen-Sensitized Mice

, 2015
Hideaki Morita, Ken Arae, Hirotoshi Unno, Sumika Toyama, Kenichiro Motomura, Akio Matsuda, Hajime Suto, Ko Okumura, Katsuko Sudo, Takao Takahashi, Hirohisa Saito, Kenji Matsumoto, Susumu Nakae   +12 more
openalex   +2 more sources

IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells [PDF]

, 2013
Steven A. Saenz, Mark C. Siracusa, Laurel A. Monticelli, Carly G.K. Ziegler, Brian Kim, Jonathan R. Brestoff, Lance W. Peterson, E. John Wherry, Ananda W. Goldrath, Avinash Bhandoola, David Artis   +10 more
openalex   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

IL-25 Treatment Improves Metabolic Syndrome in High-Fat Diet and Genetic Models of Obesity. [PDF]

Diabetes Metab Syndr Obes, 2021
Smith AD, Fan A, Qin B, Desai N, Zhao A, Shea-Donohue T.   +5 more
europepmc   +1 more source