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IL-25, another promoter of allergy
2009Although there have been significant insights into the mechanism underlying the initiation of type 1 immune response, how type 2-mediated pathology especially allergic diseases is developed remains unclear. Cytokine environment is important in shaping and initiating Th2 responses. IL-25, also called IL-17E, belongs to the IL-17 family but, unlike other
Pornpimon Angkasekwinai, Chen Dong
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Immunology & Cell Biology, 2018
AbstractInterleukin (IL)‐25 is a cytokine that has previously been shown to have a protective role against nonalcoholic fatty liver disease (NAFLD), which is associated with the induction of M2 macrophage differentiation. However, the direct relationships between IL‐25 expression regulation, M2 induction and NAFLD remain unknown.
Xue-Lian, Zheng +10 more
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AbstractInterleukin (IL)‐25 is a cytokine that has previously been shown to have a protective role against nonalcoholic fatty liver disease (NAFLD), which is associated with the induction of M2 macrophage differentiation. However, the direct relationships between IL‐25 expression regulation, M2 induction and NAFLD remain unknown.
Xue-Lian, Zheng +10 more
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Say it isn’t pso: IL-25 drives skin inflammation
Science Immunology, 2018IL-25 from keratinocytes mediates skin inflammation in psoriasis.
Lokesh A, Kalekar, Michael D, Rosenblum
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IL‐25: A key requirement for the regulation of type‐2 immunity
BioFactors, 2009AbstractIt has been well‐established that type‐2 immunity, characterized by eosinophilia, goblet cell hyperplasia, mucus production, and B cell class switching to IgE, is highly dependent on the production of the type‐2 cytokines, interleukin (IL)‐4, IL‐5, IL‐9, and IL‐13, by T helper 2 (Th2) cells.
Jillian L, Barlow, Andrew N J, McKenzie
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Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma
Journal of Allergy and Clinical Immunology, 2007IL-25 (IL-17E), a member of the IL-17 family of immunoregulatory cytokines, has been implicated in the regulation of type 2 immunity. Its roles in antigen-driven airway inflammation and airway hyperresponsiveness (AHR) remain to be fully established.We sought to determine whether a neutralizing antibody against IL-25 represents a novel therapeutic for ...
Sarah J, Ballantyne +8 more
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Increased IL-25 levels in the peritoneal fluid of patients with endometriosis
Journal of Reproductive Immunology, 2016Previous studies have indicated a higher prevalence of allergic disease among women with endometriosis. It is already well established that type 1 allergies develop in a Th2 cytokine environment. Recent studies have shown, however, that IL-25 induces a Th2 development of naive T lymphocytes and is central in the Th2 response.
Helle Folge Bungum +4 more
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Il 25 aprile dopo il 25 aprile. Istituzioni, politica, cultura
2017Il libro presenta relazioni di un convegno svoltosi presso l'Università di Roma 3 dedicato ai vari aspetti della ricorrenza del 25 aprile. I vari contributi analizzano la posizione dei vertici istituzionali e dei partiti politici nel corso del tempo, ma anche il racconto che ne hanno fatto cantautori, registi, narratori.
Carusi, Paolo, DE NICOLÒ, Marco
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IL-25 for use in the treatment of inflammatory diseases
2009The current invention relates to the regulation of cell cytokine response, in particular the cytokine response of CD 14 + cells. The cytokines are involved in the Th1 response and / or the Th-17 response. The invention further relates to the use of cytokines in the preparation of a medicament for the treatment of inflammatory disease in which CD14 ...
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