Results 271 to 280 of about 6,883,971 (302)

IL-25 and IL-25 Receptor Expression on Eosinophils from Subjects with Allergic Asthma

International Archives of Allergy and Immunology, 2013
<b><i>Background:</i></b> Allergic asthma is an inflammatory airway disease in which Th2 cytokines play an important role. Epithelial-derived interleukin (IL)-25 has been suggested to be important in the maintenance of Th2-type responses.
Tang, Wei, Smith, Steven G, Beaudin, Sue, Dua, Benny, Howie, Karen, Gauvreau, Gail, O'Byrne, Paul M   +6 more
openaire   +3 more sources

Topical Corticosteroids Decrease IL-25 Expression by Immunohistochemistry

ORL, 2019
<b><i>Background:</i></b> Interleukin-25 (IL-25) is an important contributing factor in the pathogenesis of allergic rhinitis. It leads to increasing peripheral and infiltrating eosinophilia as well as serum IgE, IgG, and Th2 cytokines (IL-4, IL-5, IL-13), which are responsible for the allergic symptoms. Intranasal steroids (INS)
Hany Samir, Moustafa, Mohamed, Qotb, Mohammed Ahmed, Hussein, Ahmed, Eid, Essam Ezzat, Ayad, Tamer, Fawzy   +5 more
openaire   +2 more sources

Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses

Journal of Allergy and Clinical Immunology, 2011
IL-25 is thought to participate in allergic inflammation by propagating T(h)2-type responses.To address the hypothesis that allergen provocation increases expression of IL-25 and its receptor IL-25R in the asthmatic bronchial mucosa and skin dermis of atopic subjects.Sequential single and double immunostaining was used to evaluate the numbers and ...
Corrigan, Chris J., Wang, Wei, Meng, Qiu, Fang, Cailong, Eid, Ghada, Caballero, M. Rosario, Lv, Ze, An, Yunqing, Wang, Yui-Hsi, Liu, Yong-Jun, Kay, A. Barry, Lee, Tak H., Sun, Ying   +12 more
openaire   +3 more sources

Say it isn’t pso: IL-25 drives skin inflammation

Science Immunology, 2018
IL-25 from keratinocytes mediates skin inflammation in psoriasis.
Lokesh A, Kalekar, Michael D, Rosenblum
openaire   +2 more sources

IL-25, another promoter of allergy

2009
Although there have been significant insights into the mechanism underlying the initiation of type 1 immune response, how type 2-mediated pathology especially allergic diseases is developed remains unclear. Cytokine environment is important in shaping and initiating Th2 responses. IL-25, also called IL-17E, belongs to the IL-17 family but, unlike other
Pornpimon Angkasekwinai, Chen Dong
openaire   +1 more source

Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma

Journal of Allergy and Clinical Immunology, 2007
IL-25 (IL-17E), a member of the IL-17 family of immunoregulatory cytokines, has been implicated in the regulation of type 2 immunity. Its roles in antigen-driven airway inflammation and airway hyperresponsiveness (AHR) remain to be fully established.We sought to determine whether a neutralizing antibody against IL-25 represents a novel therapeutic for ...
Sarah J, Ballantyne, Jillian L, Barlow, Helen E, Jolin, Puneeta, Nath, Alison S, Williams, Kian Fan, Chung, Graham, Sturton, See Heng, Wong, Andrew N J, McKenzie   +8 more
openaire   +2 more sources

IL‐25 protects against high‐fat diet‐induced hepatic steatosis in mice by inducing IL‐25 and M2a macrophage production

Immunology & Cell Biology, 2018
AbstractInterleukin (IL)‐25 is a cytokine that has previously been shown to have a protective role against nonalcoholic fatty liver disease (NAFLD), which is associated with the induction of M2 macrophage differentiation. However, the direct relationships between IL‐25 expression regulation, M2 induction and NAFLD remain unknown.
Xue-Lian, Zheng, Jian-Ping, Wu, Yue, Gong, Jun-Bo, Hong, Hai-Ying, Xiao, Jia-Wei, Zhong, Bo, Xie, Bi-Min, Li, Gui-Hai, Guo, Xuan, Zhu, An-Jiang, Wang   +10 more
openaire   +2 more sources

Combined blockade of IL‐25, IL‐33 and TSLP mediates amplified inhibition of airway inflammation and remodelling in a murine model of asthma

Respirology (Carlton South. Print), 2019
Isolated blockade of IL‐25, IL‐33 and thymic stromal lymphopoietin (TSLP) has been shown to reduce airways inflammation and hyperresponsiveness in murine asthma model.
Gao An, Wenjun Wang, Xin Zhang, Qiong Huang, Qin Li, Shihao Chen, Xiaonan Du, C. Corrigan, Kewu Huang, Wei Wang, Yan Chen, S. Ying   +11 more
semanticscholar   +1 more source

IL-25 as a Potential Therapeutic Target in Allergic Asthma

Immunotherapy, 2015
Allergic asthma is a prevalent disease characterized by intermittent airway hyperresponsiveness resulting in airway narrowing, debilitating wheezing and shortness of breath that in severe cases can prove fatal. Notably, the number of sufferers, especially among children, has increased dramatically over recent decades and the WHO estimates that 235 ...
Martin D, Knolle, Batika M, Rana, Andrew N J, McKenzie   +2 more
openaire   +2 more sources

Il 25 aprile dopo il 25 aprile. Istituzioni, politica, cultura

2017
Il libro presenta relazioni di un convegno svoltosi presso l'Università di Roma 3 dedicato ai vari aspetti della ricorrenza del 25 aprile. I vari contributi analizzano la posizione dei vertici istituzionali e dei partiti politici nel corso del tempo, ma anche il racconto che ne hanno fatto cantautori, registi, narratori.
Carusi, Paolo, DE NICOLÒ, Marco
openaire   +1 more source