Results 31 to 40 of about 1,543,952 (322)

Intelectin contributes to allergen-induced IL-25, IL-33, and TSLP expression and type 2 response in asthma and atopic dermatitis. [PDF]

, 2017
The epithelial and epidermal innate cytokines IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) have pivotal roles in the initiation of allergic inflammation in asthma and atopic dermatitis (AD).
Cheng, D, Di, H, Erle, DJ, Huo, X, Mo, Y, Shi, H, Xu, Y, Yi, L, Zhang, H, Zhang, K, Zhao, J, Zhen, G, Zou, Y   +12 more
core   +1 more source

Interleukin-25 and eosinophils progenitor cell mobilization in allergic asthma

Clinical and Translational Allergy, 2018
Background Eosinophil-lineage committed progenitor cells (EoP) migrate from the bone marrow and differentiate locally to provide an ongoing source of mature eosinophils in asthmatic inflammatory responses in the airways.
Wei Tang, Steven G. Smith, Wei Du, Akash Gugilla, Juan Du, John Paul Oliveria, Karen Howie, Brittany M. Salter, Gail M. Gauvreau, Paul M. O’Byrne, Roma Sehmi   +10 more
doaj   +1 more source

Type 2 Innate Lymphoid Cells in Allergic Disease. [PDF]

, 2013
Type II innate lymphoid cells (ILC2) are a novel population of lineage-negative cells that produce high levels of Th2 cytokines IL-5 and IL-13. ILC2 are found in human respiratory and gastrointestinal tissue as well as in skin.
Doherty, Taylor A, Lund, Sean, Walford, Hannah H   +2 more
core   +2 more sources

The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation [PDF]

, 2018
Type 2 innate lymphoid cells (ILC2s) both contribute to mucosal homeostasis and initiate pathologic inflammation in allergic asthma. However, the signals that direct ILC2s to promote homeostasis versus inflammation are unclear. To identify such molecular
A Dixit, A Jäger, A Tanay, A Wagner, AK Björklund, Antonia Wallrapp, Aviv Regev, BD Modena, Brian J. Haas, Bruce D. Levy, C Soneson, CE Prendergast, Christoph S. N. Klose, Christopher Rodman, D Cheng, Daneyal Farouq, Danielle Dionne, David Artis, DF Gudbjartsson, DR Neill, F Gerbe, GX Zheng, I Tirosh, Isaac M. Chiu, J Beale, J von Moltke, JA Hedrick, Jackson Nyman, JC Nussbaum, John J. Trombetta, JT Gaublomme, K Branchfield, K Kurakula, K Moro, K Shekhar, KJ Audrit, L Shan, LA Monticelli, LA Monticelli, M Gury-BenAri, M Moriyama, M Salimi, M Schuliga, M Singer, Matan Hofree, Michael S. Cuoco, ML Robinette, Monika S. Kowalczyk, MR Howitt, MS Kowalczyk, N Habib, NL Bray, NM Heshmat, Orit Rozenblatt-Rosen, Pankaj Baral, Patrick R. Burkett, PG Szekeres, R Satija, Raja-Elie E. Abdulnour, S Picelli, S Talbot, Samantha J. Riesenfeld, T Katsunuma, T Polte, T Sekigawa, Tanel Mahlakõiv, Timothy L. Tickle, TY Halim, Vijay K. Kuchroo, X Gu, Y Huang, YJ Chang   +71 more
core   +1 more source

In vitro Culture with Cytokines Provides a Tool to Assess the Effector Functions of ILC2s in Peripheral Blood in Asthma

Journal of Asthma and Allergy, 2021
Li Y Drake,1,2 Kathleen R Bartemes,1,3 Kay A Bachman,1 John B Hagan,1 Hirohito Kita1,4 1Division of Allergic Diseases and Department of Medicine, Mayo Clinic, Rochester, MN, USA; 2Department of Anesthesiology and Perioperative Medicine, Mayo Clinic ...
Drake LY, Bartemes KR, Bachman KA, Hagan JB, Kita H   +4 more
doaj  

A Novel IL-25 Signaling Pathway through STAT5 [PDF]

The Journal of Immunology, 2015
Abstract IL-25 is a member of the IL-17 family of cytokines that promotes Th2 cell–mediated inflammatory responses. IL-25 signals through a heterodimeric receptor (IL-25R) composed of IL-17RA and IL-17RB, which recruits the adaptor molecule Act1 for downstream signaling.
Ling, Wu, Jarod A, Zepp, Wen, Qian, Bradley N, Martin, Wenjun, Ouyang, Weiguo, Yin, Kevin D, Bunting, Mark, Aronica, Serpil, Erzurum, Xiaoxia, Li   +9 more
openaire   +2 more sources

Contemporary Murals in the Street and Urban Art Field: Critical Reflections between Preventive Conservation and Restoration of Public Art

Heritage, 2021
This paper focuses on the presentation of some of the main critical reflections concerning the current debate about conservation and restoration of contemporary murals in the Street and Urban Art field.
Paola Mezzadri
doaj   +1 more source

IL-25 regulates Th17 function in autoimmune inflammation [PDF]

The Journal of Experimental Medicine, 2007
Interleukin (IL)-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. We now show that IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–producing T cells.
Kleinschek, Melanie A., Owyang, Alexander M., Joyce-Shaikh, Barbara, Langrish, Claire L., Chen, Yi, Gorman, Daniel M., Blumenschein, Wendy M., McClanahan, Terrill, Brombacher, Frank, Hurst, Stephen D., Kastelein, Robert A., Cua, Daniel J.   +11 more
openaire   +2 more sources

Codon optimization, expression, purification, and functional characterization of recombinant human IL-25 in Pichia pastoris [PDF]

, 2013
Interleukin (IL)-25 (also known as IL-17E) is a distinct member of the IL-17 cytokine family which induces IL-4, IL-5, and IL-13 expression and promotes pathogenic T helper (Th)-2 cell responses in various organs.
Chengsheng Wu, Jinyu Wang, Min Yu, Wei Mo, Yushan Liu   +4 more
core   +1 more source

Evaluation of Sensitivity and Specificity of Interleukins 25 and 33 in Diagnosis of Pediatric Asthma

Journal of Pure and Applied Microbiology, 2021
The roles of interleukin 25 (a member of the interleukin 17 family) and interleukin 33 (a member of the interleukin 1 family) in asthma and airway hyperresponsiveness are yet to be fully understood.
Abeer Thaher Naji AL-Hasnawi
doaj   +1 more source