Results 31 to 40 of about 9,708,765 (268)

Clonorchis sinensis lysophospholipase A upregulates IL-25 expression in macrophages as a potential pathway to liver fibrosis

Parasites & Vectors, 2017
Background Liver fibrosis is an excessive wound-healing reaction that requires the participation of inflammatory cells and hepatic stellate cells (HSCs).
Lina Zhou, Mengchen Shi, Lu Zhao, Zhipeng Lin, Zeli Tang, Hengchang Sun, Tingjin Chen, Zhiyue Lv, Jin Xu, Yan Huang, Xinbing Yu   +10 more
doaj   +1 more source

Street and Urban Muralism in Public Art: Conservation Between Evolution and Research in the Methods of the Istituto Centrale per Il Restauro

Heritage
This paper presents an overview of a research line developed at the Istituto Centrale per il Restauro within the CHANGES (Cultural Heritage Active Innovation for Next-Gen Sustainable Society) project, funded under the Italian National Recovery and ...
Paola Mezzadri, Sara De Angelis, Rebecca Picca Orlandi, Michela Renna, Giancarlo Sidoti   +4 more
doaj   +1 more source

Synthetic small interfering RNAs selectively suppress the expression of proinflammatory cytokine genes (IL-25 and TSLP) in experiments in vitro

Медицинская иммунология
Allergic rhinitis (AR) is an inflammatory disease of the upper respiratory tract (nasal mucosa). AR affects up to 40% of the world’s population; in the Russian Federation, the incidence is 18% to 30%, depending on the region.
M. M. Kaganova, I. P. Shilovskiy, E. D. Timotievich, K. V. Yumashev, D. A. Gurskii, K. V. Vinogradova, M. V. Popova, M. R. Khaitov   +7 more
doaj   +1 more source

Alarmin Cytokines as Central Regulators of Cutaneous Immunity

Frontiers in Immunology, 2022
Skin acts as the primary interface between the body and the environment. The skin immune system is composed of a complex network of immune cells and factors that provide the first line of defense against microbial pathogens and environmental insults ...
Tatsuya Hasegawa, Tomonori Oka, Shadmehr Demehri   +2 more
doaj   +1 more source

New insights into the function of Interleukin-25 in disease pathogenesis

Biomarker Research, 2023
Interleukin-25 (IL-25), also known as IL-17E, is a cytokine belonging to the IL-17 family. IL-25 is abundantly expressed by Th2 cells and various kinds of epithelial cells.
Qingfang Yuan, Na Peng, Fan Xiao, Xiaofei Shi, Bo Zhu, Ke Rui, Jie Tian, Liwei Lu   +7 more
doaj   +1 more source

Revisiting the interleukin 17 family of cytokines in psoriasis: pathogenesis and potential targets for innovative therapies

Frontiers in Immunology, 2023
Psoriasis is a common chronic inflammatory skin disease, associated with substantial comorbidity. TH17 lymphocytes, differentiating under the influence of dendritic cell-derived IL-23, and mediating their effects via IL-17A, are believed to be central ...
Nicolo Costantino Brembilla, Wolf-Henning Boehncke, Wolf-Henning Boehncke   +2 more
doaj   +1 more source

Breast cancer therapy with IL-25 [PDF]

Science-Business eXchange, 2011
A U.S.-Taiwan team has shown that the proinflammatory cytokine IL-25 exerts potent cytotoxic effects in breast cancer cells and decreases mammary tumor growth in mice. The researchers and an undisclosed company will collaborate to develop systems for delivering IL-25 or its mimetics directly to tumors.
openaire   +1 more source

Regulation of IL-9 expression by IL-25 signaling [PDF]

Nature Immunology, 2010
The physiological regulation of the expression of interleukin (IL)-9, a cytokine traditionally regarded as being T(H)2 associated, remains unclear. Here, we show that IL-9-expressing T cells generated in vitro in the presence of transforming growth factor-beta and IL-4 express high levels of mRNA for IL-17 receptor B (IL-17RB), the receptor for IL-25 ...
Angkasekwinai, Pornpimon, Chang, Seon Hee, Thapa, Manoj, Watarai, Hiroshi, Dong, Chen   +4 more
openaire   +2 more sources

Biological Properties and the Role of IL-25 in Disease Pathogenesis [PDF]

Journal of Immunology Research, 2018
The interleukin- (IL-) 17 superfamily, a T cell-derived cytokine, consists of 6 ligands (IL-17A–IL-17F) and 5 receptors (IL-17RA–IL-17RE). IL-17A, a prototype member of this family, is involved in the pathogenesis of allergies, autoimmune diseases, allograft transplantations, and malignancies.
Yuwan Liu, Zewei Shao, Guoqiang Shangguan, Qingli Bie, Bin Zhang   +4 more
openaire   +3 more sources

IL-25 enhances production of IgM_Ft.

, 2021
(A) IL-25 was measured in BALF or thoracic cavity lavage 18 hrs post immunization or infection in WT B6 mice (n = 3). (B, C) WT B6 mice were treated with recombinant IL-25 and immunized i.n. with LPSFt. Seven days p.i.
Fabio Re (189981), Jinyong Wang (112096), Joseph Reynolds (3430580), Carlos Henrique D. Barbosa (11349350), Louis Lantier (499627)   +4 more
core   +1 more source