Intestinal IL-25 prevents high-fat diet-induced obesity by modulating the cholesterol transporter NPC1L1 expression in the intestinal epithelial cells [PDF]
Scientific ReportsThe intestine is essential for digestion and nutrient absorption, and its altered function contributes to metabolic dysregulation and obesity-induced intestinal inflammation.
Siranart Jeerawattanawart +1 more
doaj +2 more sources
IL-25 promotes trophoblast proliferation and invasion via binding with IL-17RB and associated with PE [PDF]
Hypertension in Pregnancy, 2021 Introduction: Interleukin-25 is a Th2 interleukin and has been shown to influence cell behavior. This study aims to illustrate its affection on extravillous trophoblasts function and association with PE.
Siyu Liu +5 more
doaj +2 more sources
Медицинская иммунология, 2021 Atopic dermatitis is one of the most common chronic inflammatory skin diseases caused by both terminal defects in keratinocyte differentiation, and pronounced type 2 immune responses.
M. B. Drozhdina, E. V. Suslova
doaj +1 more source
Table_1_Interleukin-25-Mediated-IL-17RB Upregulation Promotes Cutaneous Wound Healing in Diabetic Mice by Improving Endothelial Cell Functions.docx [PDF]
, 2022 Diabetic foot ulcer (DFU) frequently leads to non-traumatic amputation and finally even death. However, the mechanism of DFU is not fully understood.
Xin Yan (17064) +7 more
core +1 more source
Interleukin 25 and its biological features and function in intestinal diseases
Central European Journal of Immunology, 2023 Interleukin 25 (IL-25), also known as IL-17E, is a member of the IL-17 cytokine family and an important regulator of the type 2 immune response. Accumulating evidence suggests that IL-25 interacts with diverse immune as well as non-immune cells and plays
Wei Jiang +3 more
doaj +1 more source
Epithelial cell alarmin cytokines: Frontline mediators of the asthma inflammatory response
Frontiers in Immunology, 2022 The exposure of the airway epithelium to external stimuli such as allergens, microbes, and air pollution triggers the release of the alarmin cytokines IL-25, IL-33 and thymic stromal lymphopoietin (TSLP). IL-25, IL-33 and TSLP interact with their ligands,
Marc Duchesne, Isobel Okoye, Paige Lacy
doaj +1 more source
Differential Effects of Alarmins on Human and Mouse Basophils
Frontiers in Immunology, 2022 Epithelial-derived alarmins (IL-33, TSLP, and IL-25) play an upstream role in the pathogenesis of asthma. Basophil-derived cytokines are a pivotal component of allergic inflammation.
Adriana R. Gambardella +17 more
doaj +1 more source
IL-25 enhances production of IgMFt. [PDF]
, 2021 (A) IL-25 was measured in BALF or thoracic cavity lavage 18 hrs post immunization or infection in WT B6 mice (n = 3). (B, C) WT B6 mice were treated with recombinant IL-25 and immunized i.n. with LPSFt. Seven days p.i.
Fabio Re (189981) +4 more
core +1 more source
Interleukin‐25: New perspective and state‐of‐the‐art in cancer prognosis and treatment approaches
Cancer Medicine, 2021 Cancer is a leading cause of death which imposes a substantial financial burden. Among the several mechanisms involved in cancer progression, imbalance of immune cell‐derived factors such as cytokines and chemokines plays a central role.
Arezoo Gowhari Shabgah +7 more
doaj +1 more source
Arthritis Research & Therapy, 2020 Background The present study aimed to evaluate the suppressive role of interleukin (IL)-25 in IL-22-induced osteoclastogenesis and receptor activator of nuclear factor κB ligand (RANKL) expression in rheumatoid arthritis (RA). Methods Serum from patients
Hong Ki Min +7 more
doaj +1 more source