Results 61 to 70 of about 6,883,971 (302)

Mucosal immune responses following intestinal nematode infection. [PDF]

open access: yes, 2014
In most natural environments, the large majority of mammals harbour parasitic helminths that often live as adults within the intestine for prolonged periods (1-2 years).
Else KJ   +11 more
core   +4 more sources

Alarmin Cytokines as Central Regulators of Cutaneous Immunity

open access: yesFrontiers in Immunology, 2022
Skin acts as the primary interface between the body and the environment. The skin immune system is composed of a complex network of immune cells and factors that provide the first line of defense against microbial pathogens and environmental insults ...
Tatsuya Hasegawa   +2 more
doaj   +1 more source

Beneficial autoimmunity at body surfaces – immune surveillance and rapid type 2 immunity regulate tissue homeostasis and cancer [PDF]

open access: yes, 2014
Epithelial cells line body surface tissues and provide a physicochemical barrier to the external environment. Frequent microbial and non-microbial challenges such as those imposed by mechanical disruption, injury or exposure to noxious environmental ...
Agrawal   +190 more
core   +2 more sources

New insights into the function of Interleukin-25 in disease pathogenesis

open access: yesBiomarker Research, 2023
Interleukin-25 (IL-25), also known as IL-17E, is a cytokine belonging to the IL-17 family. IL-25 is abundantly expressed by Th2 cells and various kinds of epithelial cells.
Qingfang Yuan   +7 more
doaj   +1 more source

Revisiting the interleukin 17 family of cytokines in psoriasis: pathogenesis and potential targets for innovative therapies

open access: yesFrontiers in Immunology, 2023
Psoriasis is a common chronic inflammatory skin disease, associated with substantial comorbidity. TH17 lymphocytes, differentiating under the influence of dendritic cell-derived IL-23, and mediating their effects via IL-17A, are believed to be central ...
Nicolo Costantino Brembilla   +2 more
doaj   +1 more source

Regulation of IL-9 expression by IL-25 signaling [PDF]

open access: yesNature Immunology, 2010
The physiological regulation of the expression of interleukin (IL)-9, a cytokine traditionally regarded as being T(H)2 associated, remains unclear. Here, we show that IL-9-expressing T cells generated in vitro in the presence of transforming growth factor-beta and IL-4 express high levels of mRNA for IL-17 receptor B (IL-17RB), the receptor for IL-25 ...
Angkasekwinai, Pornpimon   +4 more
openaire   +2 more sources

A Novel Non-invasive Method to Detect RELM Beta Transcript in Gut Barrier Related Changes During a Gastrointestinal Nematode Infection [PDF]

open access: yes, 2019
Currently, methods for monitoring changes of gut barrier integrity and the associated immune response via non-invasive means are limited. Therefore, we aimed to develop a novel non-invasive technique to investigate immunological host responses ...
Affinass, Nicole   +8 more
core   +4 more sources

Street and Urban Muralism in Public Art: Conservation Between Evolution and Research in the Methods of the Istituto Centrale per Il Restauro

open access: yesHeritage
This paper presents an overview of a research line developed at the Istituto Centrale per il Restauro within the CHANGES (Cultural Heritage Active Innovation for Next-Gen Sustainable Society) project, funded under the Italian National Recovery and ...
Paola Mezzadri   +4 more
doaj   +1 more source

Helminth Infections: Recognition and Modulation of the Immune Response by Innate Immune Cells [PDF]

open access: yes, 2018
The survival of helminths in the host over long periods of time is the result of a process of adaptation or dynamic co-evolution between the host and the parasite. However, infection with helminth parasites causes damage to the host tissues producing the
Ambrosio, Laura Fernanda   +7 more
core   +1 more source

Breast cancer therapy with IL-25 [PDF]

open access: yesScience-Business eXchange, 2011
A U.S.-Taiwan team has shown that the proinflammatory cytokine IL-25 exerts potent cytotoxic effects in breast cancer cells and decreases mammary tumor growth in mice. The researchers and an undisclosed company will collaborate to develop systems for delivering IL-25 or its mimetics directly to tumors.
openaire   +1 more source

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