Results 81 to 90 of about 1,233,492 (271)

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source

Study of Serum IgM, IgG, IL-37 Levels and IL-37 Gene Polymorphism in Women Infected with Trichomonas Vaginalis in Baqubah City

Proceedings of the International Conference on Applied Innovations in IT
Trichomoniasis is the most prevalent non-viral sexually transmitted infection globally, relying on both innate and adaptive immunity to combat the extracellular pathogen Trichomonas vaginalis. This study included 45 infected women and 45 healthy controls
Noor Ghassan, Maha Falih Nazzal, Ibtisam Badday Hassan   +2 more
doaj   +1 more source

Increased expression of IL-37 in patients with Graves' disease and its contribution to suppression of proinflammatory cytokines production in peripheral blood mononuclear cells. [PDF]

PLoS ONE, 2014
BACKGROUND: Interleukin-37 (IL-37), a member of IL-1 family, is primarily an anti-inflammatory cytokine, which reduces systemic and local inflammation. However, the expression and role of IL-37 in Graves' disease (GD) remains unknown.
Yanqun Li, Zi Wang, Ting Yu, Bingni Chen, Jinshun Zhang, Kunzhao Huang, Zhong Huang   +6 more
doaj   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian, Robert U. Newton, Dennis R. Taaffe, Nicholas G. Gottardo, Santosh Valvi, Carolyn J. Peddle‐McIntyre, Jodie Cochrane Wilkie, Daniel A. Galvão   +7 more
wiley   +1 more source

IL-37 gene variant (rs3811047): A marker of disease activity in rheumatoid arthritis: A pilot study

Autoimmunity, 2018
Background: Rheumatoid arthritis (RA) is a joint destructive disorder with great morbidity. Unraveling genetic determinants causing the disease would pave the road towards early detection and precise medicine.
Eman H. El-Sayed, Mai H. Saleh, Mohsen H. Al-Shahaly, Eman A. Toraih, Amal Fathy   +4 more
doaj   +1 more source

Protective host defense against disseminated candidiasis is impaired in mice expressing human interleukin-37

Frontiers in Microbiology, 2015
The effect of the anti-inflammatory cytokine interleukin-37 (IL 37) on host defense against Candida infections remains unknown. We assessed the role of IL 37 in a murine model of disseminated candidiasis using mice transgenic for human IL 37 (hIL 37Tg).
Frank L. Van De Veerdonk, Frank L. Van De Veerdonk, Frank L. Van De Veerdonk, Mark S Gresnigt, Jos WM Van Der Meer, Leo eJoosten, Leo eJoosten, Mihai eNetea, Mihai eNetea, Charles eDinarello, Charles eDinarello   +10 more
doaj   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

The amelioration effect of antidiabetic agents on cytokine expression in patients with type 2 diabetes mellitus

Saudi Pharmaceutical Journal
Inflammation is a condition that is closely linked to diabetes mellitus type 2 (T2DM), short for T2DM several different antidiabetic medications have been produced to regulate hyperglycemia, with indications that these therapies may have anti ...
Abeer M. Abd El-Hameed, Areej A. Eskandrani, Eman Salah Abdel-Reheim, Adel Abdel Moneim, Wessam Addaleel   +4 more
doaj   +1 more source

Mineral reconnaissance at the Highland boundary with special reference to the Loch Lomond and Aberfoyle areas [PDF]

, 1983
Serpentinite bodies at the Highland Boundary in the Loch Lomond and Aberfoyle areas are extensively altered to magnesite-quartz and ferroan-dolomite-quartz rocks. Silicification was probably initiated before conversion to carbonate.
Fortey, N.J., Grout, A., Henderson, W.G., Johnson, C.E.   +3 more
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