Results 61 to 70 of about 6,730,203 (124)

Counteractive Effects of IL-33 and IL-37 on Inflammation in Osteoarthritis †

, 2022
Osteoarthritis (OA) is a chronic inflammatory disease where pro-inflammatory cytokines, damage-associated molecular patterns (DAMPs), and macrophages play a crucial role.
Vikrant Rai, Farial Samadi, Dilisio, Matthew F., Agrawal, Devendra K., Rai, Vikrant, Samadi, Farial, Matthew F. Dilisio, Devendra K. Agrawal   +7 more
core   +1 more source

IL-37 Expression Is Downregulated in Lesional Psoriasis Skin [PDF]

, 2020
IL-37 broadly suppresses inflammation in various disease models. However, studies of the regulation and role of IL-37 in psoriasis are limited and contradictive.
Rønholt, K., Dinarello, C.A., Iversen, L., Nielsen, A.L., Johansen, C., Fauerbye, A., López-Vales, R., Vestergaard, C.   +7 more
core   +1 more source

Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses

, 2014
Item does not contain fulltextIL-37 is a fundamental inhibitor of innate immunity. Human IL-37 has a caspase-1 cleavage site and translocates to the nucleus upon LPS stimulation.
Nold, M.F., Li, S., Rubartelli, A., Hong, J., Dinarello, C.A., Bulau, A.M., Fink, M., Bufler, P., Mansell, A., Nold-Petry, C.A., Schwerd, T.   +10 more
core   +1 more source

Emerging cytokines contribute to the clinical manifestation of carotid artery plaque formation and stability in patients with diabetes

Atherosclerosis Plus
Background: Type 2 diabetes mellitus (T2DM) promotes atherosclerosis and plaque instability through chronic inflammation and immune dysregulation. Emerging evidence implicates members of the interleukin-1 family—particularly IL-36, IL-37, and IL-38—in ...
Zhongqing Xu, James Healy, Wenhui Dong, JingJing Ding, Xiaoyi Shen, Xianzhen Feng, Jun Zhou, Rajesh Puranik, Brett D. Hambly, Shisan Bao   +9 more
doaj   +1 more source

Evaluation of IL-32 rs28372698 and IL-37 rs3811047 polymorphisms and their serum levels in rheumatoid arthritis patients

Egyptian Rheumatology and Rehabilitation
Background Interleukin (IL)-32 and IL-37 are implicated in the pathophysiology of rheumatoid arthritis (RA). The aim of this study is to investigate serum levels and the genotypes of the IL-32 and IL-37 variants (IL-32 (rs28372698) and IL-37 (rs3811047))
Marwa Abdo, Ahmed Elmaghraby, Fatma H. Abdelraouf, Hossam Elashmawy, Hala Ramadan, Eman Elsayed, Shada A. Ghoniem   +6 more
doaj   +1 more source

Blood cytokines as potential predictors of the development of SARS-CoV-2 associated pneumonia in patients with stage II ESSENTIAL hypertension

Инфекция и иммунитет
The search for predictors of the severe course of COVID-19 was relevant both during the pandemic and at the present time. The aim of the study was to analyze the relationship of cytokine levels in patients with EН before SARS-CoV-2 infection with the ...
Olga A. Radaeva, A. S. Simbirtsev, M. S. Iskandyarova, E. V. Negodnova, V. V. Kulyapkin, K. A. Krasnoglazova, V. V. Eremeev   +6 more
doaj   +1 more source

Interleukin-37 Inhibits Colon Carcinogensis During Chronic Colitis

Frontiers in Immunology, 2019
Inflammatory bowel disease increases the risk of developing colon cancer. Interleukin (IL-) 37 is a fundamental inhibitor of innate immunity by reducing systemic and local inflammation.
Steffeni Mountford, Andrea Ringleb, Rahel Schwaiger, Doris Mayr, Sebastian Kobold, Sebastian Kobold, Charles A. Dinarello, Philip Bufler, Philip Bufler   +8 more
doaj   +1 more source

Il modello di business

, 2011
Il capitolo presenta i risultati di un questionario rivolto agli intermediari bancari italiani che operano nel comparto del microcredito finalizzato ad indagare lo stato dell'arte di questo business (margini prodotti, modalità di valutazione del rischio,
PORRETTA, Pasqualina
core  

The Immunoregulatory Function of Serum Interleukin-37 and Link to Biochemical Markers of Liver Injury in Chronic HBV and HCV Infections

Baghdad Journal of Biochemistry and Applied Biological Sciences
Rendering to estimates from the World Health Organization (WHO), around 296 million people are chronically infected with HBV, while approximately 58 million live with chronic HCV infection globally .In the present study, 100 patients diagnosed with ...
Rana Talib Mohsen, Sally Hassan
doaj   +1 more source

The Possible Role of the Novel Cytokines IL-35 and IL-37 in Inflammatory Bowel Disease [PDF]

, 2014
Interleukin- (IL-) 35 and IL-37 are newly discovered immune-suppressing cytokines. They have been described in inflammatory diseases such as collagen-induced arthritis and asthma.
Yanqing Li, Yanan Wang, Ying Liu, Xuefeng Lu, Yatian Wang, Xiuli Zuo, Yanmei Li   +6 more
core   +1 more source