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Anti-IL-5 Vaccination Dampens Allergen-Specific IgE Levels and Modulates IL-4 and IL-5 Th2 Cytokines in Skin Allergy of Mice and Horses. [PDF]
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Science's STKE, 2005
Interleukin-4 (IL-4) is a cytokine produced by T H 2 type helper T cells and by mast cells, basophils, and eosinophils. This cytokine can elicit many responses, some of which are associated with allergy and asthma. Studies with long-term cell lines and primary cells have revealed differences in the signaling between
Ann, Kelly-Welch +2 more
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Interleukin-4 (IL-4) is a cytokine produced by T H 2 type helper T cells and by mast cells, basophils, and eosinophils. This cytokine can elicit many responses, some of which are associated with allergy and asthma. Studies with long-term cell lines and primary cells have revealed differences in the signaling between
Ann, Kelly-Welch +2 more
openaire +2 more sources
CD28 Costimulation Accelerates IL-4 Receptor Sensitivity and IL-4-Mediated Th2 Differentiation
The Journal of Immunology, 1999Abstract The development of Th1 and Th2 cells is determined by the type of antigenic stimulation involved in the initial cell activation step. Evidence indicates that costimulatory signals, such as those delivered by CD28, play an important role in Th2 development, but little is known about how CD28 costimulation contributes to Th2 ...
M, Kubo +6 more
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The Journal of Immunology, 1996
Abstract Alternative splicing of mRNA can generate protein isoforms that are preferentially expressed in different tissues or during different states of cell differentiation or activation. Protein isoforms may have different functions.
S P, Atamas +3 more
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Abstract Alternative splicing of mRNA can generate protein isoforms that are preferentially expressed in different tissues or during different states of cell differentiation or activation. Protein isoforms may have different functions.
S P, Atamas +3 more
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Aspirin inhibits IL-4 production
Trends in Immunology, 2001The anti-inflammatory properties of aspirin are well-recognized and have been chiefly attributed to the effect of aspirin on prostaglandins. It is known that aspirin inhibits cyclo-oxygenase, the enzyme which catalyzes the production of prostaglandin from cell-membrane fatty-acid precursors.
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2021
The distribution of SNP C-589 (rs2243250) of the promoter region of the regulatory cytokine IL-4 gene was analyzed with the help of the pilot research among patients of the pulmonary department of the Adygeya Republican Clinical Hospital who had given their informed consent (n = 11, average age 45). They had severe mixed forms of bronchial asthma (BA)
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The distribution of SNP C-589 (rs2243250) of the promoter region of the regulatory cytokine IL-4 gene was analyzed with the help of the pilot research among patients of the pulmonary department of the Adygeya Republican Clinical Hospital who had given their informed consent (n = 11, average age 45). They had severe mixed forms of bronchial asthma (BA)
openaire +1 more source