Results 131 to 140 of about 96,694,076 (289)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
, 2011 Il capitolo presenta i risultati di un questionario rivolto agli intermediari bancari italiani che operano nel comparto del microcredito finalizzato ad indagare lo stato dell'arte di questo business (margini prodotti, modalità di valutazione del rischio,
PORRETTA, Pasqualina
core
AntibodiesBackground: Asthma exhibits marked heterogeneity both clinically and at the molecular phenotypic level, requiring specifically targeted treatments to block the key pathways of the disease.
Garry M. Walsh
doaj +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
IL-4 and FoxP3+ Treg IL-4Rα (CD124) mediates Treg IL-10 production.
, 2019 FoxP3+ Tregs and RbLoTem were stimulated in co-culture as before for 3 days with the addition of cytokine (A) or receptor (B) neutralizing antibodies to identify the mediator of IL-10 synergy.
Nathan Morris (2696935) +5 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
IL-4 and IL-13-polarized M2 macrophages are deficient in IL-10 and CCL17 secretion.
, 2018 (A) Differential cytokine secretion profiles of M1 macrophages and M2 macrophages exposed to IL-4 and IL-13. (B) Differential cell surface marker expression. MFI indicates mean fluorescence intensity. (C) Differential gene expression. For panels A and C,
Elizabeth M. Jaffee (183374) +5 more
core +1 more source
Association of IL‐33 in modeling type‐2 airway inflammation and pulmonary emphysema in mice
Immunity, Inflammation and DiseaseWe developed pulmonary emphysema and a type 2 airway inflammation overlap mouse model. The bronchoalveolar lavage (BAL) interleukin 13 (IL‐13), IL‐4, and IL‐5 levels in the overlap model were higher than in the pulmonary emphysema model and lower than in
Chika Miyaoka +11 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source