Results 111 to 120 of about 2,017,899 (336)

Schistosoma mansoni in IL-4-deficient mice [PDF]

, 2017
Immunopathology and Immune responses to Schistosoma mansoni were examined in IL-4 -/- mice. IL-5 and IL-10 production by lymphoid cells stimulated with soluble egg antigen (SEA), peripheral eosinophilla and serum levels of soluble IL-4 receptor but not ...
Cheever, Allen, Covalesky, Maria, Fernandez-Botran, Raphael, Kohler, Georges, Kopt, Manfred, Leonard, Susan, Pearce, Edward J.   +6 more
core  

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Cytokines in Allergic Conjunctivitis: Unraveling Their Pathophysiological Roles

Life
Allergic conjunctivitis is one of the common immune hypersensitivity disorders that affect the ocular system. The clinical manifestations of this condition exhibit variability contingent upon environmental factors, seasonal dynamics, and genetic ...
DeGaulle I. Chigbu, Nicholas J. Karbach, Sampson L. Abu, Navpreet K. Hehar   +3 more
doaj   +1 more source

Enhanced extraction of organophosphorus pesticides from fruit juices using magnetic effervescent tablets composed of the NiFe₂O₄@SiO₂@PANI-IL nanocomposites

, 2021
Dechao Chen, Sai Ma, Xiaofan Zhang, Xuedong Wang, Ming Gao, Jieyi Li, Huili Wang   +6 more
openalex   +2 more sources

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. [PDF]

, 1989
We purified poly(A)+ mRNA from the spleen and lymph nodes at designated times after infection with Leishmania major in genetically susceptible BALB/c and resistant C57BL/6 mice.
Coffman, RL, Heinzel, FP, Holaday, BJ, Locksley, RM, Sadick, MD   +4 more
core  

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source

Impaired IL-4 and c-Maf expression and enhanced Th1-cell development in Vav1-deficient mice [PDF]

, 2005
Yoshihiko Tanaka, Takanori So, Svetlana Lebedeva, Michael Croft, Amnon Altman   +4 more
openalex   +1 more source

Diphenyl ether as prospective interleukin-4 synthetic analogs' precursor [PDF]

, 2017
Interleukin-4 (IL-4) is a multifunctional cytokine secreted by a number of cells. IL-4 drives Th2- mediated allergy response; its overproduction leads to the development of atopic diseases. On the other hand, M2-like macrophages generated in the presence
Катаева, В. А., Станкевич, Ксения Сергеевна   +1 more
core  

Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek, Lori Wiener, Stephanie Veldhuijzen van Zanten, Donna Johnston, Fyeza Hasan, Adam Rapoport, Nathasha Datoo, Kimberley Widger, Sumit Gupta, Karen Fergus, Anthony K. C. Chan, Alisha Kassam, Emily McCullogh, Dave Lysecki   +13 more
wiley   +1 more source