ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess +5 more
wiley +1 more source
IL-2, IL-4, IL-6, and IL-10 levels of children with nosocomial A. baumannii complex.
IL-2, IL-4, IL-6, and IL-10 levels of children with nosocomial A. baumannii complex.
Xuejun Chen (255765) +2 more
core +1 more source
Изучение взаимодействия IL-4 и IL-4δ2 с рецепторами IL-4R I и II типов in silico и их эффектов на функциональную активность мононуклеарных клеток in vitro [PDF]
Alternatively spliced interleukins are very actively studied over the last years. Splice form of IL-4 — IL-4δ2 has antagonistic effects to its full form on proliferative activity of human mononuclear blood cells and their IL-6 production.
K. V. Goremykin +11 more
core +1 more source
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu +8 more
wiley +1 more source
IL-4/IL-13 independent goblet cell hyperplasia in experimental helminth infections-3
Bar) and IL-4/IL-13(gray bar) mice at 8 weeks PI. Data are pooled from 2 to 4 individual experiments. Data are means of these experiments ± SEM. (B) Quantification of goblet cell number per villus in colon of naïve mice and 8 weeks PI from BALB/c (solid ...
Lizette CE Fick (58853) +7 more
core +1 more source
Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham +7 more
wiley +1 more source
Although IL-4 is long associated with CD4 Th2 immune responses, its role in Th2 subset development in non-lymphoid tissues is less clear. We sought to better define IL-4’s role in CD4 Th2 responses by using transgenic mice that express a dual IL-4 AmCyan/
Franca Ronchese (78627) +3 more
core +1 more source
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh +4 more
wiley +1 more source
IL-27 regulates IL-18 binding protein in skin resident cells [PDF]
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M +23 more
core +2 more sources
Effects of BCG Vaccination Prior to Specific Immunotherapy on IL-4/IFN-γ Ratio and AR Total Symptom Score in Persistent Allergic Rhinitis (Efek vaksinasi BCG pre imunoterapi spesifik terhadap rasio IL-4/IFN-γ dan skor gejala total rinitis pada rinitis alergi persisten) [PDF]
Background: Allergic disease including allergic rhinitis (AR) is dominated by Th2 responses with increased production of IL-4 and inhibition of IFN-ï§ production. BCG vaccination induced IL-12 production which promotes Th0 to Th1 shift and stimulates IFN-
Suprihati , Suprihati
core +1 more source

