Results 81 to 90 of about 96,694,076 (289)
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz +6 more
wiley +1 more source
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad +9 more
wiley +1 more source
Ex Vivo Cytokine mRNA Levels Correlate with Changing Clinical Status of Ethiopian TB Patients and their Contacts Over Time [PDF]
There is an increasing body of evidence which suggests that IL-4 plays a role in the pathogenesis of TB, but a general consensus on its role remains elusive.
Tilahun, Hiwot +34 more
core +1 more source
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen +10 more
wiley +1 more source
IL-4, but not interferon-γ expression is deficient in iNKT cells from SLE patient.
(A) A representative histogram of flow cytometric analysis for intracellular staining of interferon-γ (IFN-γ) and interleukin-4(IL-4). Comparison was made between SLE patients and normal controls (Normal).
Pei-Tzu Lee (4510087) +6 more
core +1 more source
An interleukin 4 (IL-4)-independent pathway for CD4 + T cell IL-4 production is revealed in IL-4 receptor-deficient mice [PDF]
IL-4 receptor α chain (IL-4Rα)-deficient mice were generated by gene-targeting in BALB/c embryonic stem cells. Mutant mice showed a loss of IL-4 signal transduction and functional activity. The lack of IL-4Rα resulted in markedly diminished, but not absent, TH2 responses after infection with the helminthic parasite
Noben, Trauth N +5 more
openaire +2 more sources
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau +8 more
wiley +1 more source
Mechanisms by which interleukin-4 suppresses inflammatory cytokine production by activated human monocytes [PDF]
Improving understanding of how inflammatory responses by monocytes and macrophages are regulated may aid in the development of more targeted therapies for chronic inflammatory disease.
Woodward, Eleanor
core
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source
IL-4 and IL-13 increased collagen 1 gene transcription and collagen types I-V protein expression.
A. Total RNA purified from N1 or SFT1 prostate fibroblasts cultured in serum-free media supplemented with vehicle or 20ng/ml IL-4, IL-13, or 4ng/ml TGF-β, for 24 hours with or without 2 hr pre-treatment with 400 ng/ml IL-4Rα or 40 ng/ml IL-13Rα1 antibody
Mehrnaz Gharaee-Kermani (118877) +3 more
core +1 more source

