Results 81 to 90 of about 18,242,260 (289)

An interleukin 4 (IL-4)-independent pathway for CD4 ⁺ T cell IL-4 production is revealed in IL-4 receptor-deficient mice [PDF]

Proceedings of the National Academy of Sciences, 1997
IL-4 receptor α chain (IL-4Rα)-deficient mice were generated by gene-targeting in BALB/c embryonic stem cells. Mutant mice showed a loss of IL-4 signal transduction and functional activity. The lack of IL-4Rα resulted in markedly diminished, but not absent, TH2 responses after infection with the helminthic parasite
Noben, Trauth N, Shultz, L D, Brombacher, F, Urban, J F, Gu, H, Paul, W E   +5 more
openaire   +2 more sources

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

The level of IL-12, IL-10, IL-4, and MMP-13 in cutaneous leishmaniasis patients

Medical Journal of Babylon
Background: Cutaneous leishmaniasis (CL) is a dermatological condition that arises due to the presence of protozoan parasites. The disease disproportionately impacts those residing in economically disadvantaged regions and is closely linked to factors ...
Abrar Kareem Dhari, Ali Mohammed Abed, Suha Maher Abed   +2 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

IL-4 cytokine concentrations.

, 2019
Production of IL-4 cytokine in supernatants during Specific (HPV, SEA and SWAP) and non-specific stimulation (CONA) and absence of stimulant (MED) in Schisto-infected+HPV, Schisto/PZQ+HPV vaccine and HPV-only (Control) groups.
Vicky Gent (7310216), Lucy Ochola (7310222), Thomas Kariuki (271512), Rebecca Waihenya (709338), Lucy Kamau (3514073), Ruth Nyakundi (7310219), Peris Ambala (4376563)   +6 more
core   +1 more source

Mice deficient in interleukin-4 (IL-4) or IL-4 receptor alpha have higher resistance to sporozoite infection with Plasmodium berghei (ANKA) than do naive wild-type mice [PDF]

, 2004
BALB/c interleukin-4 (IL-4(-/-)) or IL-4 receptor-alpha (IL-4ralpha(-/-)) knockout (KO) mice were used to assess the roles of the IL-4 and IL-13 pathways during infections with the blood or liver stages of plasmodium in murine malaria.
Andreas Krueger, Sandra Arriens, Volker Heussler, Fleischer, Bernhard, Heussler, Volker, Brombacher, Frank, Michael Saeftel, Bernhard Fleischer, Saeftel, Michael, Arriens, Sandra, Hoerauf, Achim, Krueger, Andreas, Frank Brombacher, Racz, Paul, Paul Racz, Achim Hoerauf   +15 more
core   +1 more source

Effects of BCG Vaccination Prior to Specific Immunotherapy on IL-4/IFN-γ Ratio and AR Total Symptom Score in Persistent Allergic Rhinitis (Efek vaksinasi BCG pre imunoterapi spesifik terhadap rasio IL-4/IFN-γ dan skor gejala total rinitis pada rinitis alergi persisten) [PDF]

, 2009
Background: Allergic disease including allergic rhinitis (AR) is dominated by Th2 responses with increased production of IL-4 and inhibition of IFN-ï§ production. BCG vaccination induced IL-12 production which promotes Th0 to Th1 shift and stimulates IFN-
Suprihati , Suprihati
core   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Immunomodulatory effect of hepatitis B virus (HBV) antigens and MRSA antigens on immune response

Medical Journal of Babylon
Background: Methicillin-resistant Staphylococcus aureus is one of the most common human invaders and causes different types of illness worldwide.
Entidhar A. Hadi, Mohammad Abd-Kadhum Al-Saadi, Kaiser N. Madlum   +2 more
doaj   +1 more source

Increase in serum IL-4 in response to venetoclax therapy in xenograft models of acute myeloid leukaemia

Медицинская иммунология
Despite significant progress in basic and preclinical research into acute myeloid leukaemia (AML), the five-year survival rate for patients with AML remains poor, highlighting the urgent need for new combination therapies. Over the past decade, increased
D. A. Bogdanova, V. V. Shindyapin, E. D. Kolosova, T. V. Pukhalskaya, N. A. Budkina, A. A. Shatilova, O. N. Demidov   +6 more
doaj   +1 more source