Results 261 to 270 of about 2,017,899 (336)

Real -Time PCR analysis for transcripts of suppressers (IL-4 and GATA-3) and enhancers (IFN-α) of IL-12Rβ2 mRNA in 28 tuberculosis patients and healthy volunteers.

, 2015
Vikas Kumar Verma (327546), Vibha Taneja, Jaiswal Anand, Sangeeta Sharma, Digamber Behera, Sreenivas Vishnubhatla, Shyam Singh Chauhan (181368), Hanumanthappa Krishna Prasad (327552)   +7 more
openalex   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

IL-4/STAT6-signaling Influences Local Inflammation and Regeneration Processes During Acute Pancreatitis and Promotes Fibrosis by a Direct Activation of Pancreatic Fibroblasts During Chronic Pancreatitis. [PDF]

Adv Sci (Weinh)
ElSheikh H, Salvers A, Piesker J, Buchholz S, Lange R, Ameling S, Steil L, Hammer E, Homuth G, Völker U, Bröker BM, Weiss FU, Sendler M, Glaubitz J.   +13 more
europepmc   +1 more source

Immune and allergic responses to Anisakis pegreffii, with focus on the roles of IL-4, IL-13 and the IL-4 receptor alpha

, 2007
Natalie E. Nieuwenhuizen
openalex   +1 more source

Bando di concorso, per titoli ed esami, per la copertura a tempo indeterminato e pieno di n. 20 posti di OPERATORE DEL MERCATO E SERVIZI PER IL LAVORO, Area degli Istruttori per le sedi provinciali di Belluno, Padova, Treviso, Venezia, Verona e Vicenza con riserva di n. 4 posti ai sensi della L. 68/99, n. 2 posti ai sensi dell'art. 1, c. 9 bis del D.L. 44/2023 e n. 4 posti ai sensi dell'art. 1014, c1. e dell'art. 678 c 9 del D.lgs. 66/2010 - Veneto

Easy Quizzz
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Characterization and biocompatibility evaluation of a Ti@HA-GO@IL-4 bioactive composite coating for guided bone regeneration in dental implant applications. [PDF]

BMC Oral Health
Li C, Zhao L, Chen X, Aierken A, Yu M, Kong C, Baheti W.   +6 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

CD44v5 enhances the IL-4/IL-4Rα/STAT6/SAM68 aix inducing M2 polarization and promoting triple-negative breast cancer progression. [PDF]

Cancer Biol Ther
Ji Z, Wang L, Bao X, Dai Y, Jiang M, Ma H, Li N, Yang C.   +7 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source